535937-76-9

Basic information

• Product Name: 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester
• Synonyms: 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester
• CAS NO: 535937-76-9
• Molecular Weight: 417.409
• Mol File: 535937-76-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester(535937-76-9)
• EPA Substance Registry System: 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester(535937-76-9)

Safety Data

• Hazardous Substances Data: 535937-76-9(Hazardous Substances Data)

Upstream product

• 128293-62-9 ethyl 4-amino-1-methylimidazole-2-carboxylate 
• 535937-59-8 4-nitrophenyl-2-(4-trifluoromethylphenylthio)ethyl carbonate 
• 109012-23-9 ethyl 1-methyl-4-nitroimidazole-2-carboxylate 
• 98-56-6 4-chlorobenzotrifluoride 
• 535937-56-5 2-(4-trifluoromethyl-phenylsulfanyl)-ethanol 

Downstream Products

• 535937-85-0 1-methyl-4-[2-(4-trifluoromethyl-benzenesulfonyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid 
• 535937-79-2 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid 

Relevant articles and documents

The 2-(4-trifluoromethylphenylsulfonyl)ethoxycarbonyl (Tsc) amino-protecting group: Use in the solid-phase synthesis of pyrrole-imidazole polyamides

The development of the 2-(4-trifluoromethylphenylsulfonyl)ethoxycarbonyl (Tsc) function, a novel base-sensitive amino-protecting group, and its application to the preparation of DNA-binding polyamides are described. Pyrrole-imidazole polyamides were synthesized by an efficient solid-phase method under conditions compatible with Fmoc chemistry using two Tsc-protected amino acids, Tsc-Py-OH 1a and Tsc-Im-OH 1b.