128387-03-1

Basic information

• Product Name: N-((E)-(1S,2R)-2-Hydroxy-1-hydroxymethyl-heptadec-3-enyl)-acetamide
• CAS NO: 128387-03-1
• Molecular Weight: 341.535
• Mol File: 128387-03-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((E)-(1S,2R)-2-Hydroxy-1-hydroxymethyl-heptadec-3-enyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((E)-(1S,2R)-2-Hydroxy-1-hydroxymethyl-heptadec-3-enyl)-acetamide(128387-03-1)
• EPA Substance Registry System: N-((E)-(1S,2R)-2-Hydroxy-1-hydroxymethyl-heptadec-3-enyl)-acetamide(128387-03-1)

Safety Data

• Hazardous Substances Data: 128387-03-1(Hazardous Substances Data)

Upstream product

• 114697-01-7 (+/-)-N-(4t-pentadec-1-ynyl-2r-phenyl-[1,3]dioxan-5t-yl)-acetamide 
• 114697-01-7 (+/-)-N-(4c-pentadec-1-ynyl-2r-phenyl-[1,3]dioxan-5c-yl)-acetamide 
• 94676-99-0 N-((1RS,2RS)-2-hydroxy-1-hydroxymethyl-heptadec-3-ynyl)-acetamide 
• 2482-37-3 (+/-)-erythro-1,3-diacetoxy-2-acetylamino-octadec-4c-ene 
• 94676-99-0 N-((1RS,2SR)-2-hydroxy-1-hydroxymethyl-heptadec-3-ynyl)-acetamide 

Downstream Products

• 6036-86-8 (-)-L-threo-sphinganine 
• 128387-05-3 triacetyl-D-threo-sphingosine 
• 2482-37-3 (+/-)-threo-1,3-diacetoxy-2-acetylamino-octadec-4c-ene 
• 2482-37-3 (+/-)-erythro-1,3-diacetoxy-2-acetylamino-octadec-4c-ene 

Relevant articles and documents

A novel, efficient synthesis of (±)-erythro-sphingosine

A stereoselective synthesis of (±)-erythro-sphingosine triacetate (1) is described. The key reaction that determines the right stereochemistry is the iodocyclization of 1-trichloroacetimido-(2E,4E)-octadecadiene (5). The 4,5-dihydro-1,3-oxazine (6) through cleavage with HCl and treatment with Amberlyst A 26 in the AcO- form, followed by full acetylation, affords (1) in good yield.