128454-32-0

Basic information

• Product Name: 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-(trityloxyamino)acetamido]-3-vinylcephem-4-carboxylic acid
• Synonyms: 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-(trityloxyamino)acetamido]-3-vinylcephem-4-carboxylic acid
• CAS NO: 128454-32-0
• Molecular Weight: 637.74
• Mol File: 128454-32-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-(trityloxyamino)acetamido]-3-vinylcephem-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-(trityloxyamino)acetamido]-3-vinylcephem-4-carboxylic acid(128454-32-0)
• EPA Substance Registry System: 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-(trityloxyamino)acetamido]-3-vinylcephem-4-carboxylic acid(128454-32-0)

Safety Data

• Hazardous Substances Data: 128454-32-0(Hazardous Substances Data)

Upstream product

• 64276-70-6 (6R,7R)-3-Bromomethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 64485-82-1 (Z)-ethyl 2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetate 
• 28240-15-5 3-hydroxymethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 15690-38-7 (6R,7R)-7-amino-3-hydroxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 69689-86-7 ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tritylhydroxyimino)acetate 
• 94796-13-1 diphenylmethyl 7β-phenylacetamido-3-vinyl-3-cephem-4-carboxylate 
• 35246-64-1 (6R,7R)-benzhydryl 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 123201-39-8 diphenylmethyl 7β-[2-(2-tritylaminothiazol-4-yl)-(Z)-2-tritylhydroxyimino]-3-vinyl-3-cephem-4-carboxylate 

Downstream Products

• 71091-93-5 3-methyl cefdinir 
• 934986-48-8 Cefdinir sulfoxide 
• 91832-40-5 cefdinir 

Relevant articles and documents

Novel compounds for the synthesis of Cefdinir

(Chemical Equation Presented) Preparation of two new compounds 2-mercapto-5-methyl-1,3,4-thiadiazolyl-(Z)-2-(2-amino-4-thiazolyl) -2-trityloxyiminoacetate (14) and 2-mercapto-5-methyl-1, 3,4-thiadiazolyl- (Z)-2-(2-amino-4-thiazolyl)-2-acetyloxyiminoacetate (12) and their use in the preparation of 7β-[(Z)-2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3- vinylcephem-4-carboxylic acid, also known by the generic name Cefdinir (1) has been accomplished in a single step by coupling with 7-amino-3-vinylcephem-4- carboxylic acid (7) with purity of greater than 99% by HPLC.