128483-26-1

Basic information

• Product Name: 2-Mercapto-4-p-chlorophenyl-4H-1,2,3,4,5,6-hexahydrobenzo-quinazoline
• Synonyms: 2-Mercapto-4-p-chlorophenyl-4H-1,2,3,4,5,6-hexahydrobenzo-quinazoline
• CAS NO: 128483-26-1
• Molecular Weight: 326.849
• Mol File: 128483-26-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-Mercapto-4-p-chlorophenyl-4H-1,2,3,4,5,6-hexahydrobenzo-quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Mercapto-4-p-chlorophenyl-4H-1,2,3,4,5,6-hexahydrobenzo-quinazoline(128483-26-1)
• EPA Substance Registry System: 2-Mercapto-4-p-chlorophenyl-4H-1,2,3,4,5,6-hexahydrobenzo-quinazoline(128483-26-1)

Safety Data

• Hazardous Substances Data: 128483-26-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 17356-08-0 thiourea 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 49545-70-2 E-2-(4-chlorobenzylidene)-1-tetralone 
• 49545-70-2 2-(4-chlorobenzylidene)-3,4-dihydronaphthalen-1(2H)-one 

Downstream Products

• 128483-43-2 6-p-chlorophenyl-6H-2,3,7,8-tetrahydrobenzo-1,3-thiazine-<2,3-b>quinazoline-3-one 
• 128483-39-6 7-(4-Chloro-phenyl)-9-methyl-5,7-dihydro-6H-10-thia-7a,11-diaza-cyclopenta[b]phenanthren-8-one 
• 128483-30-7 5-p-chlorophenyl-5H-2,3,6,7-tetrahydrobenzothiazolo<2,3-b>quinazoline-3-one 
• 1628075-48-8 10-((5-bromo-1H-indol-3-yl)methylene)-7-(4-chlorophenyl)-7,10-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolin-9(6H)-one 
• 1628075-47-7 7-(4-chlorophenyl)-10-((5-methoxy-1H-indol-3-yl)methylene)-7,10-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolin-9(6H)-one 
• 368846-07-5 10-((1H-indol-3-yl)methylene)-7-(4-chlorophenyl)-7,10-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolin-9(6H)-one 
• 1628075-46-6 7-(4-chlorophenyl)-10-((2-methyl-1H-indol-3-yl)methylene)-7,10-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolin-9(6H)-one 
• 1628798-82-2 3-(7-(4-chlorophenyl)-6,7-dihydro-5H-benzo[h]thiazolo[2,3-b]-quinazolin-9-yl)-2H-chromen-2-one 
• 1628798-71-9 7,9-bis(4-chlorophenyl)-6,7-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazoline 
• 128483-34-1 2-(p-chlorophenylmethylene)-5-p-chlorophenyl-5H-2,3,6,7-tetrahydrobenzothiazolo<2,3-b>quinazoline-3-one 

Relevant articles and documents

One-pot synthesis, biological evaluation and molecular docking studies of fused thiazolo[2,3-b]pyrimidinone-pyrazolylcoumarin hybrids

Abstract: As a part of our endeavor toward the synthesis of a new class of biologically potent heterocyclic hybrids, a series of newly fused thiazolo[2,3-b]pyrimidinones bearing a pyrazolylcoumarin moiety (6a–p) were synthesized in acceptable yields. Anti

Base-mediated one-pot synthesis of 3,4,5,6-tetrahydro-4-substituted benzo[h]quinazoline-2(1H)-thione derivatives and evaluation of their antioxidant activity

One-pot three-component Beginelli-like reactions of a ketone 1, an aryl aldehyde 2, and thiourea 3 in the presence of sodium hydroxide are described. In this reaction, 3,4,5,6-tertrahydro-4-substituted quinazoline-2(1H)-thione derivatives 4a–h were obtain

Benzo[h]thiazolo[2,3-b]quinazolines by an efficient p-toluenesulfonic acid-catalyzed one-pot two-step tandem reaction

A highly efficient method has been developed for synthesis of 7,9-disubstituted-6,7-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolines via multicomponent one-pot two-step tandem reaction involving 1-tetralone, arylaldehydes, thiourea, and 4-chlorophenacyl bromide/(3-bromoacetyl)coumarin utilizing p-toluenesulfonic acid as catalyst in glacial acetic acid under reflux conditions. Analytically pure products are formed with excellent yield and short reaction time. All the synthesized compounds were confirmed by their spectral and elemental analyses. Graphical abstract: [Figure not available: see fulltext.]