128947-01-3

Basic information

• Product Name: (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone
• Synonyms: (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone
• CAS NO: 128947-01-3
• Molecular Weight: 258.32
• Mol File: 128947-01-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone(128947-01-3)
• EPA Substance Registry System: (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone(128947-01-3)

Safety Data

• Hazardous Substances Data: 128947-01-3(Hazardous Substances Data)

Upstream product

• 625-35-4 trans-chrotonyl chloride 
• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 10487-71-5 crotonyl chloride 
• 24221-86-1 (+)-(1S,2R)-ephedrine hydrochloride 

Downstream Products

• 128863-72-9 (4R,5S)-1,5-Dimethyl-3-((R)-3-methyl-hex-5-enoyl)-4-phenyl-imidazolidin-2-one 
• 183074-26-2 (4R,5S)-1,5-Dimethyl-3-((2S,3R)-3-methyl-aziridine-2-carbonyl)-4-phenyl-imidazolidin-2-one 
• 176791-95-0 (4R,5S)-1,5-Dimethyl-3-((2R,3S)-3-methyl-aziridine-2-carbonyl)-4-phenyl-imidazolidin-2-one 
• 331283-98-8 (4R,5S)-1,5-dimethyl-3-[(1S,2S,3R,4R)-3-methylbicyclo[2.2.1]hept-5-en-2-ylcarbonyl]-4-phenyl-2-imidazolidinone 
• 139962-49-5 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((S)-3-p-tolyl-butyryl)-imidazolidin-2-one 
• 113675-84-6 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((S)-3-phenyl-butyryl)-imidazolidin-2-one 
• 113675-86-8 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((R)-3-phenyl-butyryl)-imidazolidin-2-one 
• 139962-60-0 (4S,5R)-1-((S)-3,5-Dimethyl-hex-4-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 139962-60-0 (4S,5R)-1-((R)-3,5-Dimethyl-hex-4-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 139962-59-7 (4S,5R)-1-((S)-3,4-Dimethyl-pent-4-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 139962-59-7 (4S,5R)-1-((R)-3,4-Dimethyl-pent-4-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 139962-66-6 (4R,5S)-1,5-Dimethyl-3-((S)-3-methyl-pent-4-enoyl)-4-phenyl-imidazolidin-2-one 
• 139962-58-6 (4R,5S)-1,5-Dimethyl-3-((R)-3-methyl-pent-4-enoyl)-4-phenyl-imidazolidin-2-one 
• 139962-52-0 (4R,5S)-1,5-Dimethyl-3-((R)-3-methyl-hexanoyl)-4-phenyl-imidazolidin-2-one 

Relevant articles and documents

A novel method for the N-acylation of (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one

An efficient synthesis of N-Acylimidazolidinones derived from α,β-unsaturated acid chlorides using DABCO as the base is described.

A Practical and Efficient Large-Scale Preparation of (4R,58)-N-Propenoyl-1,5-dimethyl-4-phenylimidazolidin-2-one. A Simple Procedure for the Preparation of N-Acylimidazolidin-2-ones and N-Acylbornane 2,10-Sultams

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Asymmetric 1,4-addition of Grignard reagents to chiral α,β-unsaturated imides in the presence of Lewis acids

The asymmetric 1,4 addition of PhMgCl, MeMgBr and allylMgBr to chiral imides 1 has been studied under various conditions. The presence of a Lewis acid, as AlMe2Cl, affords an enhanced diastereoselectivity favouring the formation of the product derived from the attack on the re face. The 1,4 addition of allyl diisopropoxyborate to imides 1 has also been analysed.