1293408-37-3

Basic information

• Product Name: C₂₃H₃₀O₇Si
• Synonyms: C₂₃H₃₀O₇Si
• CAS NO: 1293408-37-3
• Molecular Weight: 446.572
• Mol File: 1293408-37-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₃₀O₇Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₃₀O₇Si(1293408-37-3)
• EPA Substance Registry System: C₂₃H₃₀O₇Si(1293408-37-3)

Safety Data

• Hazardous Substances Data: 1293408-37-3(Hazardous Substances Data)

Upstream product

• 484-52-6 isoapiole 
• 7731-10-4 4,7-dimethoxybenzo[d][1,3]dioxole-5-carboxylic acid 
• 17055-09-3 4,7-dimethoxy-benzo[1,3]dioxole-5-carbaldehyde 
• 523-80-8 apiol 
• 1160476-25-4 C₁₃H₁₂N₂O₅ 
• 1293408-32-8 N-methoxy-N-methyl-2,5-dimethoxy-3,4-methylenedioxybenzamide 
• 177329-71-4 5-Bromo-1-(tert-butyldimethylsilyloxy)-2-methoxybenzene 

Downstream Products

• 1293408-42-0 (3-hydroxy-4-methoxyphenyl)(2,5-dimethoxy-3,4-methylenedioxyphenyl)methanone 

Relevant articles and documents

Application of plant allylpolyalkoxybenzenes in synthesis of antimitotic phenstatin analogues

Phenstatin and its derivatives with the modified ring A have been synthesized, using plant allylpolyalkoxybenzenes as a starting material. The targeted molecules were evaluated in a phenotypic sea urchin embryo assay for antiproliferative activity. It was found that phenstatin ring A modifications yielded antimitotic compounds. The most effective myristicin derivative 7d (combretastatin A-2 analogue) was determined to be ca. 10 times more potent than phenstatin, displaying antimitotic tubulin-destabilizing activity at the same concentration range as combretastatins. In contrast to combretastatins, 7d featured the steric stability with potential for further design as anticancer agent.