129765-95-3 Usage
Description
3-TERT-BUTOXYCARBONYLAMINO-3-METHYL-BUTYRIC ACID, also known as (2E)-5-(tert-Butyloxycarbonylamino)-5-methylhex-2-enoic Acid (B809765), is an intermediate compound used in the synthesis of various pharmaceuticals. It is a white powder with specific chemical properties that make it a valuable component in the development of certain drugs.
Uses
Used in Pharmaceutical Industry:
3-TERT-BUTOXYCARBONYLAMINO-3-METHYL-BUTYRIC ACID is used as an intermediate in the synthesis of (2E)-5-(tert-Butyloxycarbonylamino)-5-methylhex-2-enoic Acid (B809765) for the preparation of C-terminal sulfonamide analogs of NN703. These analogs serve as growth hormone secretagogues, which are compounds that stimulate the release of growth hormone in the body.
The application of this compound in the pharmaceutical industry is primarily due to its role in the synthesis of growth hormone secretagogues, which have potential therapeutic applications in the treatment of various conditions related to growth hormone deficiency or imbalance.
Check Digit Verification of cas no
The CAS Registry Mumber 129765-95-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,6 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 129765-95:
(8*1)+(7*2)+(6*9)+(5*7)+(4*6)+(3*5)+(2*9)+(1*5)=173
173 % 10 = 3
So 129765-95-3 is a valid CAS Registry Number.
129765-95-3Relevant articles and documents
NOVEL FERROPORTIN INHIBITORS
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Page/Page column 321, (2017/05/10)
The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
3-Amino-N-adamantyl-3-methylbutanamide derivatives as 11β- hydroxysteroid dehydrogenase 1 inhibitor
Lee, Younho,Shin, Yong June,Ahn, Soon Kil
, p. 1421 - 1425 (2014/03/21)
Many adamantane derivatives have been demonstrated to function as 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors. 3-Amino-N-adamantyl-3-methylbutanamide derivatives were optimized by structure-based drug design. Compound 8j exhibited a good in vitro and ex vivo inhibitory activity against both human and mouse 11β-HSD1.
NOVEL PYRIDINE DERIVATIVES
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Page/Page column 43, (2013/02/27)
The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.