129789-64-6

Basic information

• Product Name: 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate
• Synonyms: 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate
• CAS NO: 129789-64-6
• Molecular Weight: 868.796
• Mol File: 129789-64-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate(129789-64-6)
• EPA Substance Registry System: 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate(129789-64-6)

Safety Data

• Hazardous Substances Data: 129789-64-6(Hazardous Substances Data)

Upstream product

• 199597-29-0 C₃₄H₃₆N₃O₈PS 
• 94-99-5 2,4-Dichlorobenzyl chloride 
• 98796-51-1 5'-O-(4,4'-dimethoxytrityl)-2'-deoxythymidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite] 
• 59293-67-3 2,4-dichlorobenzyl mercaptan 

Downstream Products

• 118149-27-2 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate 
• 129789-68-0 triethylammonium O-<5'-O-(4,4'-dimethoxytrityl)-thymidin-3'-yl> S-(2,4-dichlorobenzyl) phosphorodithioate 
• 129789-69-1 Thymidine-3'-O-<β-cyanoethyl-(S-2,4-dichlorobenzyl)>-phosphorodithioate 
• 129789-70-4 C₅₈H₅₇Cl₄N₅O₁₃P₂S₄ 

Relevant articles and documents

Solution phase synthesis of dithymidine phosphorodithioate using new S- protecting groups in combination with a chemoselective coupling reagent (PyNOP)

A method for the synthesis of O-thymidin-3'-yl S-alkyl dithiophosphate monomers 1 with different S-protecting groups has been developed. These have been used for solution phase synthesis of dithymidine phosphorodithioate by a new phosphotriester method. C

Synthesis of dinucleoside and dinucleotide phosphorodithioates via a phosphotriester approach

5′ -O-Dimethoxytrityl and S-protected thymidine-3′ -phosphorodithioate, 3′ -O-acetylthymidine or thymidine-3′ -O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate, 1-methylimidazole, and 2,4,6-triisopropylbenzenesulfonylchloride react to give excel