59293-67-3

Basic information

• Product Name: 2,4-DICHLOROBENZYL MERCAPTAN
• Synonyms: 2,4-DICHLORO-ALPHA-TOLUENETHIOL;2,4-DICHLORO-ALPHA-MERCAPTOTOLUENE;2,4-DICHLOROBENZYL MERCAPTAN;2,4-DICHLOROTHIOBENZYL ALCOHOL;(2,4-Dichlorophenyl)methanethiol;Benzenemethanethiol, 2,4-dichloro-;2,4-dichlorotoluene-alpha-thiol;2,4-Dichlorobenzylmercaptane
• CAS NO: 59293-67-3
• Molecular Formula: C₇H₆Cl₂S
• Molecular Weight: 193.09
• EINECS: 261-687-2
• Mol File: 59293-67-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 150-151°C 12mm
• Flash Point: 150-151°C/12mm
• Appearance: /
• Density: 1,36 g/cm3
• Vapor Pressure: 0.0139mmHg at 25°C
• Refractive Index: 1.6045
• Water Solubility: Insoluble in water
• Sensitive: Air Sensitive
• BRN: 509602
• CAS DataBase Reference: 2,4-DICHLOROBENZYL MERCAPTAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLOROBENZYL MERCAPTAN(59293-67-3)
• EPA Substance Registry System: 2,4-DICHLOROBENZYL MERCAPTAN(59293-67-3)

Safety Data

• Statements: 20/21/22
• Safety Statements: 23-26-36/37/39
• RIDADR: 2810
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 59293-67-3(Hazardous Substances Data)

Usage

General Description

2,4-Dichlorobenzyl mercaptan is a chemical compound commonly used as a synthetic intermediate in the production of various organic chemicals. It is a colorless to pale-yellow liquid with a strong, unpleasant odor and is mainly employed as a building block for the synthesis of pharmaceuticals, pesticides, and other specialty chemicals. In addition, it is also used as a reagent in organic synthesis to introduce the 2,4-dichlorobenzyl group into various organic molecules. However, it is important to handle this chemical with care, as it is toxic and can cause irritation to the skin, eyes, and respiratory system. It is also considered to be a hazardous material and should be stored and handled in accordance with safety regulations.

InChI:InChI=1/C7H6Cl2S/c8-6-2-1-5(4-10)7(9)3-6/h1-3,10H,4H2

Upstream product

• 28249-28-7 dimethyl-dithiocarbamic acid-(2,4-dichloro-benzyl ester) 
• 188065-31-8 2,4-dichloro-1-{[(2,4-dichlorobenzyl)disulfanyl]methyl}benzene 
• 94-99-5 2,4-Dichlorobenzyl chloride 
• 17356-08-0 thiourea 
• 72214-67-6 S-(2,4-dichlorobenzyl)isothiourea hydrochloride 
• 131887-63-3 [(2,4-Dichloro-benzylsulfanyl)-dimethylamino-methylene]-dimethyl-ammonium; iodide 
• 1777-82-8 (2,4-dichlorophenyl)methanol 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 41022-54-2 ethyl 2-(2, 4-dichlorophenyl)acetate 
• 129789-64-6 5'-O-Dimethoxytritylthymidine-3'-O-[β-cyanoethyl-(S-2,4-dichlorobenzyl)]-phosphorodithioate 
• 119595-47-0 C₄₈H₄₇Cl₂N₄O₇PS 
• 116872-59-4 5'-O-tritylthymidine-3'-O(S-2,4 dichlorobenzylmethyl)methylphosphonothioate 
• 119595-46-9 C₄₂H₄₄Cl₂N₃O₇PS 
• 119595-51-6 C₄₉H₄₇Cl₂N₆O₆PS 
• 119595-55-0 C₄₆H₄₉Cl₂N₆O₇PS 
• 73024-13-2 17α-<(2,4-dichlorobenzyl)thio>-1,4-androstadiene-3,11-dione 
• 75663-55-7 4-(2-fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine 
• 72364-69-3 4-(2,4-Dichloro-benzylsulfanyl)-4-(2-fluoro-phenyl)-1-methyl-piperidine 
• 119619-08-8 O-(5'-O-(dimethoxytrityl)thymidin-3'-yl) S-(2,4-dichlorobenzyl) N,N-dimethyl thiophosphoramidite 
• 119595-50-5 C₄₆H₄₅Cl₂N₄O₇PS 
• 119595-54-9 C₄₇H₄₅Cl₂N₆O₆PS 
• 119595-58-3 C₄₄H₄₇Cl₂N₆O₇PS 

Relevant articles and documents

Nonenzymatic Dynamic Kinetic Resolution of in situ Generated Hemithioacetals: Access to 1,3-Disubstituted Phthalans

The first nonenzymatic DKR reaction of hemithioacetals is developed. Hemithioacetals were formed in situ via thiol addition and subsequently underwent an intramolecular oxa-Michael reaction. The scope of the reaction was quite broad ranging from aliphatic to aromatic substituents and 1,3-disubstituted-1,3-dihyroisobenzofuran products were obtained in good yields with moderate diastereoselectivities and high enantioselectivities. (Figure presented.).

Solid Supported Reagents and Reactions. Part 21.1 Rapid and Clean Synthesis of Thiols from Halides Using Polymer-supported Hydrosulfide

A variety of thiols are prepared from corresponding halides using polymer-supported hydrosulfide in excellent yields. Isolation of pure products by simple filtration and evaporation is an important feature of this method.

Sulfur-containing imidazoles

Novel imidazole mercaptals of the formula STR1 wherein each m is independently zero or one; and R1 and R2 each are independently selected from (lower)alkyl, cycloalkyl, cycloalkyl(lower)alkyl, phenyl, phenyl(lower)alkyl, thienyl, thienyl(lower)alkyl, pyridyl and pyridyl(lower)alkyl, in which the phenyl and heterocyclic rings optionally may contain from 1 to 3 substituents, and acid addition salts thereof, are useful antimicrobial agents.