129961-95-1

Basic information

• Product Name: 2-(4-phenylsulfanyl-benzenesulfonyl)acetic acid methyl ester
• Synonyms: 2-(4-phenylsulfanyl-benzenesulfonyl)acetic acid methyl ester
• CAS NO: 129961-95-1
• Molecular Weight: 322.406
• Mol File: 129961-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-phenylsulfanyl-benzenesulfonyl)acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-phenylsulfanyl-benzenesulfonyl)acetic acid methyl ester(129961-95-1)
• EPA Substance Registry System: 2-(4-phenylsulfanyl-benzenesulfonyl)acetic acid methyl ester(129961-95-1)

Safety Data

• Hazardous Substances Data: 129961-95-1(Hazardous Substances Data)

Upstream product

• 369-51-7 4-fluorobenzenesulfinic acid 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 226396-71-0 2-(4-fluorobenzenesulfonyl)acetic acid methyl ester 
• 108-98-5 thiophenol 

Relevant articles and documents

Discovery of Small-Molecule Inhibitors of the ATPase Activity of Human Papillomavirus E1 Helicase

The Boehringer Ingelheim compound collection was screened for inhibitors of the ATPase activity of human papillomavirus E1 helicase to develop antiviral agents that inhibit human papillomavirus (HPV) DNA replication. This screen led to the discovery of (biphenyl-4-sulfonyl)acetic acid 1, which inhibits the ATPase activity of HPV type 6 E1 helicase with a low micromolar IC50 value. A hit-to-lead exercise rapidly converted 1 into a low nanomolar lead series.