130112-64-0

Basic information

• Product Name: methyl 3-(4-fluorophenylamino)-3-oxopropanoate
• Synonyms: methyl 3-(4-fluorophenylamino)-3-oxopropanoate
• CAS NO: 130112-64-0
• Molecular Formula: C₁₀H₁₀FNO₃
• Molecular Weight: 211.1897032
• Mol File: 130112-64-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 3-(4-fluorophenylamino)-3-oxopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-fluorophenylamino)-3-oxopropanoate(130112-64-0)
• EPA Substance Registry System: methyl 3-(4-fluorophenylamino)-3-oxopropanoate(130112-64-0)

Safety Data

• Hazardous Substances Data: 130112-64-0(Hazardous Substances Data)

Upstream product

• 37517-81-0 3-chloro-3-oxopropanoic acid methyl ester 
• 371-40-4 4-fluoroaniline 
• 1185251-60-8 methyl N-(4-fluorophenyl)ketenimine-1-carboxylate 

Downstream Products

• 95262-10-5 3-((4-fluorophenyl)amino)-3-oxopropanoic acid 
• 1206801-43-5 ethyl 1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 888721-65-1 1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 

Relevant articles and documents

PYRIDONE COMPOUNDS AND METHODS OF USE IN THE MODULATION OF A PROTEIN KINASE

The present disclosure relates generally to compounds and pharmaceutical compositions suitable as modulators of protein kinases, and methods for their use in treating disorders mediated, at least in part by, protein kinases.

AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET

The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.

N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases

A family of thieno[3,2-b]pyridine based small molecule inhibitors of c-Met and VEGFR2 were designed based on lead structure 2. These compounds were shown to have IC50 values in the low nanomolar range in vitro and were efficacious in human tumo