130127-81-0

Basic information

• Product Name: (E)-6-phenylhex-2-en-1-ol
• Synonyms: (E)-6-phenylhex-2-en-1-ol
• CAS NO: 130127-81-0
• Molecular Weight: 176.258
• Mol File: 130127-81-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-6-phenylhex-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-6-phenylhex-2-en-1-ol(130127-81-0)
• EPA Substance Registry System: (E)-6-phenylhex-2-en-1-ol(130127-81-0)

Safety Data

• Hazardous Substances Data: 130127-81-0(Hazardous Substances Data)

Upstream product

• 18328-11-5 3-benzyl propionaldehyde 
• 55283-02-8 methyl (E)-6-phenyl-2-hexenoate 
• 1823-14-9 5-phenyl-1-pentyne 
• 77877-57-7 6-phenyl-2-hexyn-1-ol 
• 10353-53-4 1,2-epoxy-5-hexene 
• 591-50-4 iodobenzene 
• 84299-17-2 ethyl (E)-6-phenylhex-2-enoate 

Downstream Products

• 1266551-62-5 (E)-triisopropyl((6-phenylhex-2-en-1-yl)oxy)silane 
• 1266551-45-4 (E)-1-(triisopropylsilyl)-6-phenylhex-2-enyl 4-nitrobenzoate 
• 1266551-49-8 (E)-1-(triisopropylsilyl)-6-phenylhex-1-en-3-yl 4-nitrobenzoate 
• 1266551-85-2 (E)-1-(triiospropylsilyl)-6-phenylhex-1-en-3-ol 
• 1266551-87-4 (E)-1-(triisopropylsilyl)-6-phenylhex-2-enyl 4-nitrobenzoate 
• 1266551-89-6 dimethyl(phenyl)((1E,3E/Z)-6-phenylhexa-1,3-dienyl)silane 
• 1266551-46-5 C₂₇H₂₉NO₄Si 
• 1266551-50-1 C₂₇H₂₉NO₄Si 
• 1266551-91-0 (R,E)-1-(dimethyl(phenyl)lsilyl)-6-phenylhex-1-en-3-ol 
• 1266551-92-1 (E)-1-(dimethyl(phenyl)silyl)-6-phenylhex-2-enyl-4-nitrobenzoate 
• 1266551-94-3 trimethyl((1E,3E/Z)-6-phenylhexa-1,3-dienyl)silane 
• 1266551-47-6 (S,E)-1-(trimethylsilyl)-6-phenylhex-2-enyl 4-nitrobenzoate 

Relevant articles and documents

Stereoselective Carbocyclization of Vinyloxiranes Catalyzed by Lewis Acids: Construction of the Musellarin Tricyclic Core

Stereoselective carbocyclizations of vinyloxiranes were efficiently catalyzed by Lewis acids to provide cyclic homoallyl alcohols as single isomers. The choice of Lewis acid, B(C6F5)3 was crucial for the stereoselective tr

Stereoselective anti-SN2′ Mitsunobu reaction of α-hydroxy-α-alkenylsilanes

A novel silyl group-directed anti-SN2′ reaction of allylic alcohols under Mitsunobu reaction conditions is described. The Mitsunobu reaction of α-hydroxy-α-alkenylsilanes with a TBS or TIPS group gave the anti-SN2′ product, in which regio- and stereochemical outcomes of the reaction depended on the steric bulkiness of the silyl group.

(+)-Zaragozic acid C: Synthesis and related studies

The asymmetric synthesis of the potent squalene synthase inhibitor (+)-zaragozic acid C is described. The synthesis allows for the preparation of multigram quantities of the dioxabicyclooctane core common to all members of this class of fungal metabolites. Supporting studies include (1) the use of [Cr(OAc)2·H2O]2 for the stereoselective reduction of ynones to trans enones, (2) an investigation of the diastereoselective dihydroxylation of γ-alkoxy-α,β-trans enones, and (3) nucleophilic addition of Me3SiC≡CLi to a dioxabicyclooctanone, wherein the product diastereoselectivity is observed to vary as a function of cosolvents (tertiary amines) and additives (LiBr). In addition, an acylation protocol is reported which permits the regioselective installation of the C(6) O-acyl side chain.