13039-56-0

Basic information

• Product Name: 5-DEOXY-L-ARABINOSE
• Synonyms: 5-DEOXY-L-ARABINOSE;5-Methyl-tetrahydro-furan-2,3,4-triol;L-5-Deoxyarabinose;5-Deoxy-L-arabinosone;L-Arabinose, 5-deoxy-;(2R,3S,4S)-2,3,4-trihydroxypentanal
• CAS NO: 13039-56-0
• Molecular Formula: C₅H₁₀O₄
• Molecular Weight: 134.1305
• EINECS: 1533716-785-6
• Product Categories: Carbohydrates & Derivatives
• Mol File: 13039-56-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 294.479 °C at 760 mmHg
• Flash Point: 146.128 °C
• Appearance: /
• Density: 1.315 g/cm³
• Refractive Index: 1.565
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 5-DEOXY-L-ARABINOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-DEOXY-L-ARABINOSE(13039-56-0)
• EPA Substance Registry System: 5-DEOXY-L-ARABINOSE(13039-56-0)

Safety Data

• Hazardous Substances Data: 13039-56-0(Hazardous Substances Data)

Usage

Description

5-Deoxy-L-arabinose is a monosaccharide, a type of carbohydrate, that is structurally similar to L-arabinose but with one less oxygen atom. It is an important building block in the synthesis of various biologically active compounds and has potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
5-Deoxy-L-arabinose is used as a key intermediate in the synthesis of various pharmaceutical compounds, including antibiotics, antivirals, and anticancer drugs. Its unique structure allows for the development of novel drugs with improved efficacy and reduced side effects.
Used in Food Industry:
5-Deoxy-L-arabinose is used as a natural sweetener and bulking agent in the food industry. Its low glycemic index makes it a suitable alternative for people with diabetes or those looking to reduce their sugar intake.
Used in Cosmetic Industry:
5-Deoxy-L-arabinose is used as a humectant and moisturizing agent in cosmetic products. Its ability to retain moisture helps to keep the skin hydrated and maintain its elasticity.
Used in Enzyme Inhibition:
5-Deoxy-L-arabinose shows a strong inhibitory effect on β-galactosidase of Escherichia coli. This property can be utilized in various applications, such as the development of new antibiotics or the study of enzyme mechanisms.

InChI:InChI=1/C5H10O4/c1-2-3(6)4(7)5(8)9-2/h2-8H,1H3/t2-,3?,4+,5?/m0/s1

Upstream product

• 132130-06-4 L-arabino-3,4,5-triacetoxy-1,1-bis-ethanesulfonyl-hex-1-ene 
• 82970-19-2 (2S,3S,4S)-6,6-bis(ethylsulfonyl)-hex-5-ene-2,3,4-triol 
• 54253-49-5 1,1-diethylsulfonyl-L-rhamnose 
• 13039-80-0 5-deoxy-L-(+)-arabinose-diethylmercaptal 
• 93978-94-0 5-deoxy-β-L-arabinose 
• 93978-95-1 5-deoxy-α-L-arabinose 
• 488-28-8 L-rhamnitol 
• 7732-18-5 water 
• 13039-79-7 5-tosyl-L-(+)-arabinose-diethylmercaptal 
• 6748-70-5 L-rhamnose diethyl dithioacetal 
• 24807-89-4 2,3,4,5-tetra-O-acetyl-L-rhamnose diethyl dithioacetal 
• 3615-41-6 L-Rhamnose 
• 1352707-53-9 1',3'-propanedisulfonyl (L)-rhamnose 
• 43179-48-2 L-arabinose di(ethylthio)acetal 

Downstream Products

• 22150-76-1 biopterin 
• 76647-70-6 (3R,4R,5S)-3,4-dihydroxy-5-methyldihydrofuran-2(3H)-one 
• 13039-60-6 L-erythro-5-deoxy-[2]pentosulose-bis-phenylhydrazone 
• 5531-26-0 L-erythro-5-deoxy-[2]pentosulose-bis-(4-bromo-phenylhydrazone) 
• 93978-94-0 5-deoxy-β-L-arabinose 
• 93978-95-1 5-deoxy-α-L-arabinose 
• 59245-36-2 5-deoxy-L-arabinose phenylhydrazone 
• 59245-36-2 (2S,3S,4S)-1-(Phenyl-hydrazono)-pentane-2,3,4-triol 
• 95895-36-6 5-deoxy-2,3,4-O-triacetyl-L-arabinose-phenylhydrazone 
• 62933-57-7 1',2'-O-diacetyl-L-biopterin 
• 94591-24-9 Biolumazin 
• 94591-29-4 2-N-Benzoyl-1',2'-di-O-benzoylbiopterin 
• 94591-31-8 2-N-Benzoyl-1',2'-di-O-benzoyl-4-thiobiopterin 
• 2636-52-4 L-Primapterin 

Relevant articles and documents

Pterin chemistry: A simple synthesis of 5-deoxy-L-[5-2H1]arabinose and L-[3'-2H1]biopterin

A simple synthesis of 5-deoxy-L-[5-2H1]arabinose was performed to obtain L-[3'-2H1]biopterin. The reduced form of this model substance is needed to investigate the pathway of 7-substituted pterins in patients with primapterinuria.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES

The invention relates to the compounds of formula I, formula II and formula III or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II or formula III; and methods for treating or preventing metabolic diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of phenylketonuria, cardiovascular disease, autism, ADHD, hypertension, endothelial dysfunction and chronic kidney disease.

PROCESS FOR THE PREPARATION OF PTERIDINE DERIVATIVES

The application discloses a process for the preparation of 5-deoxy-L-arabinose of formula (VI); comprising the conversion of a compound of formula (XII); wherein n is 0, 1 or 2; which can be used as intermediate for the synthesis of sapropterin.