59245-36-2Relevant articles and documents
COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES
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Paragraph 0168; 0177; 0178, (2015/11/18)
The invention relates to the compounds of formula I, formula II and formula III or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II or formula III; and methods for treating or preventing metabolic diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of phenylketonuria, cardiovascular disease, autism, ADHD, hypertension, endothelial dysfunction and chronic kidney disease.
Method for producing L-biopterin
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Page/Page column 5, (2008/06/13)
To provide a method for producing L-biopterin on a large industrial scale by using a reagent which is inexpensive and easy to handle, without requiring a use of any particular equipment or plants.
169. Pterinechemistry Part 84 A New, Regiospecific Synthesis of L-Biopterin
Schircks, Bernhard,Bieri, Jost H.,Viscontini, Max
, p. 1639 - 1643 (2007/10/02)
Pure L-biopterin was obtained in 42percent yield by the condensation of 5-deoxy-L-arabinose-phenylhydrazone-triacetate with 4-hydroxy-2,5,6-triaminopyrimidine, followed by iodine oxidation of the formed tetrahydropterin derivative to 1',2'-O-diacetyl-L-biopterin.Deacetylation was carried out with NH4OH.