13057-17-5 Usage
Description
Bromomethyl methyl ether, also known as 1-bromo-methoxymethane, is a colorless liquid with the chemical formula CH3BrOCH3. It is an organic compound that is primarily used as a reagent in the protection of hydroxyl (OH) groups in various chemical reactions.
Uses
1. Used in Chemical Synthesis:
Bromomethyl methyl ether is used as a reagent for the protection of hydroxyl (OH) groups, converting them into methoxymethyl (MOM) ethers. This protection is crucial in preventing unwanted side reactions during the synthesis process.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, bromomethyl methyl ether is utilized in the enantiocontrolled synthesis of intermediates containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. This immunosuppressant is widely used to prevent organ transplant rejection and to treat certain autoimmune diseases.
3. Used in Organic Chemistry Research:
Bromomethyl methyl ether has been employed in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone, a compound that serves as a key intermediate in the development of various pharmaceuticals and organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 13057-17-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,5 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13057-17:
(7*1)+(6*3)+(5*0)+(4*5)+(3*7)+(2*1)+(1*7)=75
75 % 10 = 5
So 13057-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C2H5BrO/c1-4-2-3/h2H2,1H3
13057-17-5Relevant articles and documents
A mechanistic dehydration study with [2-13C]-DIMBOA
Hao, Huang,Sieler, Joachim,Sicker, Dieter
, p. 466 - 469 (2002)
Dehydration of a 2-13C-labeled synthetic sample of the natural aglucone 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one ([2-13C]-DIMBOA, 10) using N-ethoxycarbonyltrichloroacetaldimine led to 3-formyl-6-methoxybenzoxazolin-2(3H)-one (13C-labeled FMBOA, 11) with complete transfer of the 13C label into the -CHO group. On the basis of this finding, a mechanism for the dehydration is proposed.
FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES
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Page/Page column 79, (2012/07/13)
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, (Formula 1 should be inserted here) wherein Q is O or S; Z1 and Z2 are each independently CR9 or N; and R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
Chloropyridylcarbonyl derivatives
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, (2008/06/13)
Novel chloropyridylcarbonyl derivatives of the formula STR1 in which Het is STR2 n is 1 or 2, R1 is hydrogen, optionally substituted C1-6 alkyl, optionally substituted C2-6 alkenyl, optionally substituted C3-6 alkynyl, optionally substituted phenyl or optionally substituted pyrimidinyl, and R2 and R3, independently of each other, are hydrogen or C1-4 alkyl, and acid addition salts and metal salt complexes thereof, are outstandingly active as microbicides.
