1307863-29-1Relevant articles and documents
Organocatalytic asymmetric halogenation/semipinacol rearrangement: Highly efficient synthesis of chiral α-oxa-quaternary β-haloketones
Chen, Zhi-Min,Zhang, Qing-Wei,Chen, Zhi-Hua,Li, Hui,Tu, Yong-Qiang,Zhang, Fu-Min,Tian, Jin-Miao
, p. 8818 - 8821 (2011/07/30)
A novel asymmetric halogenation/semipinacol rearrangement reaction catalyzed by cinchona alkaloid derivatives was developed. Two types of β-haloketones (X = Br, Cl) were obtained with up to 95% yield and 99% enantiomeric excess. The desired (+) and (-) enantiomers of the β-haloketones were readily obtained.