1309982-12-4

Basic information

• Product Name: 23-(1,4'-bipiperidine-1-carbonyloxy)betulinic acid
• Synonyms: 23-(1,4'-bipiperidine-1-carbonyloxy)betulinic acid
• CAS NO: 1309982-12-4
• Molecular Weight: 666.985
• Mol File: 1309982-12-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 23-(1,4'-bipiperidine-1-carbonyloxy)betulinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 23-(1,4'-bipiperidine-1-carbonyloxy)betulinic acid(1309982-12-4)
• EPA Substance Registry System: 23-(1,4'-bipiperidine-1-carbonyloxy)betulinic acid(1309982-12-4)

Safety Data

• Hazardous Substances Data: 1309982-12-4(Hazardous Substances Data)

Upstream product

• 103816-19-9 4-piperidinopiperidine-1-carbonyl chloride 
• 85999-40-2 23-hydroxybetulinic acid 

Relevant articles and documents

Synthesis and antiproliferative evaluation of 23-hydroxybetulinic acid derivatives

Based on structural modifications of the natural 23-hydroxybetulinic acid, a series of novel its derivatives had been synthesized. The new compounds were screened for in vitro antiproliferative activity against cancer cell lines HeLa, MCF-7, HepG2, B16 and A375 using doxorubicin as a reference. The vast majority of derivatives had exhibited potent tumor growth inhibitory activity than original compound. The derivatives 4, 5, 7, 20, 23, 26, 43 and 44 with IC 50 values lower than 10 μM on all tested cell lines were regarded as the most promising compounds. The structure-activity relationships of 23-hydroxybetulinic acid derivatives were also discussed in the present investigations.