131356-52-0

Basic information

• Product Name: Benzonitrile, 4-(2,2-dibromoethenyl)-
• CAS NO: 131356-52-0
• Molecular Formula: C9H5Br2N
• Molecular Weight: 286.953
• Mol File: 131356-52-0.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-(2,2-dibromoethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(2,2-dibromoethenyl)-(131356-52-0)
• EPA Substance Registry System: Benzonitrile, 4-(2,2-dibromoethenyl)-(131356-52-0)

Safety Data

• Hazardous Substances Data: 131356-52-0(Hazardous Substances Data)

Upstream product

• 109-99-9 tetrahydrofuran 
• 157729-39-0 4-(2-bromoethynyl)-benzonitrile 
• 105-07-7 4-cyanobenzaldehyde 
• 558-13-4 carbon tetrabromide 

Downstream Products

• 79149-50-1 2-(4-cyanophenyl)-1-(piperidin-1-yl)ethanone 
• 79149-49-8 4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzonitrile 
• 60592-58-7 (Z)-4-(2-bromovinyl)benzonitrile 
• 1344717-57-2 (E)-4-(2-(9-benzyl-6-(benzylthio)-9H-purin-8-yl)vinyl)benzonitrile 
• 27973-41-7 4-((9H-fluoren-9-ylidene)methyl)benzonitrile 
• 29822-79-5 4-(2-phenylethynyl)benzonitrile 
• 62856-06-8 4-[2-(4-methylphenyl)ethynyl]benzonitrile 
• 3032-92-6 4-cyanophenylacetylene 
• 82594-67-0 4-(2-bromovinyl)benzonitrile 
• 41231-26-9 (Z)-4-(3,3-dimethylbut-1-en-1-yl)benzonitrile 
• 41231-25-8 (E)-4-(3,3-dimethylbut-1-en-1-yl)benzonitrile 

Relevant articles and documents

A Radical-Initiated Fragmentary Rearrangement Cascade of Ene-Ynamides to [1,2]-Annulated Indoles via Site-Selective Cyclization

Straightforward access to [1,2]-annulated indoles, key substructures in natural products, is highly desirable yet challenging. Herein, a radical triggered fragmentary cyclization cascade reaction of ene-ynamides is presented, providing a rapid access into [1,2]-annulated indoles by an intermolecular radical addition, intramolecular cyclization, desulfonylative aryl migration, and site-selective C(sp2)-N cyclization sequence. DFT calculations support oxidation of N-centered radical species to cations prior to the C-N bond formation, followed by an unusual aza-Nazarov cyclization.

N -tert-butyl -2 -phenylindole derivative Preparation method and application

The invention belongs to the technical field of organic synthesis, and particularly relates to N - tert-butyl -2 -phenyl indole derivatives as well as a preparation method and application thereof. The preparation method comprises the following steps: (Z)-1 - bromo -1 - phenyl -2 - styrene derivative, N, N - di-tert-butyl diazepinone, palladium catalyst, monophosphine ligand, hydrocarbon activator, base and first solvent, and N -tert-butyl -2 -aryl indole derivatives which can synthesize substituent type diversity, and the prepared N -tert-butyl -2 -aryl indole derivative can be used for preparing biologically active molecules N -2 .

The hydrodebromination of 1,1-dibromoalkenes via visible light catalysis

Vinyl bromides are versatile synthetic intermediates and widely applied in organic synthesis and pharmaceuticals. Herein, a hydrodebromination reaction of 1,1-dibromoalkenes was established via visible light catalysis. A variety of structurally different vinyl bromides were obtained in moderate to excellent yields.