60592-58-7

Basic information

• Product Name: Benzonitrile, 4-(2-bromoethenyl)-, (Z)-
• CAS NO: 60592-58-7
• Molecular Formula: C9H6BrN
• Molecular Weight: 208.057
• Mol File: 60592-58-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-(2-bromoethenyl)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(2-bromoethenyl)-, (Z)-(60592-58-7)
• EPA Substance Registry System: Benzonitrile, 4-(2-bromoethenyl)-, (Z)-(60592-58-7)

Safety Data

• Hazardous Substances Data: 60592-58-7(Hazardous Substances Data)

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 131356-52-0 2,2-dibromo-1-(4-cyanophenyl)ethene 
• 16642-94-7 (E)-4-cyanocinnamic acid 

Downstream Products

• 3032-92-6 4-cyanophenylacetylene 
• 607376-27-2 (Z,Z)-1-(2-bromophenyl)-6-(4-cyanophenyl)-1,5-hexadien-3-yne 
• 1189570-63-5 (Z)-ethyl 9-(4-cyanophenyl)non-8-enoate 
• 1239663-65-0 4-(4-(trifluoromethoxy)styryl)benzonitrile 

Relevant articles and documents

The hydrodebromination of 1,1-dibromoalkenes via visible light catalysis

Vinyl bromides are versatile synthetic intermediates and widely applied in organic synthesis and pharmaceuticals. Herein, a hydrodebromination reaction of 1,1-dibromoalkenes was established via visible light catalysis. A variety of structurally different vinyl bromides were obtained in moderate to excellent yields.

Pd-Catalyzed Difluoromethylation of Vinyl Bromides, Triflates, Tosylates, and Nonaflates

Pd-catalyzed difluoromethylation of di-, tri- or tetra-substituted vinyl bromides, triflates, tosylates and nonaflates under mild conditions is described. The reaction tolerates a wide range of functional groups, such as bromide, chloride, fluoride, ester, amine, nitrile, and protected carbonyl, thus providing a general route for the preparation of difluoromethylated alkenes. Vinyl fantasy: Pd-catalyzed difluoromethylation of di-, tri-, or tetra-substituted vinyl bromides, triflates, tosylates, and nonaflates under mild conditions is described. The reaction tolerates a wide range of functional groups, such as bromide, chloride, fluoride, ester, amine, nitrile, and protected carbonyl, thus providing a general route for the preparation of difluoromethylated alkenes.

Efficient Synthesis of Biindenylidene Derivatives via a Domino-Heck-Type Double Cyclization of Diaryldienynes

(Equation presented) Synthesis of aromatic ring substituted (E)-1,1′-biindenylidene derivatives was achieved by a domino-Heck type double cyclization of (Z,Z)-1,6-diaryl-1,5-hexadien-3-ynes.