131423-38-6

Basic information

• Product Name: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-
• CAS NO: 131423-38-6
• Molecular Formula: C17H15NO2
• Molecular Weight: 265.312
• Mol File: 131423-38-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(131423-38-6)
• EPA Substance Registry System: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(131423-38-6)

Safety Data

• Hazardous Substances Data: 131423-38-6(Hazardous Substances Data)

Upstream product

• 78396-00-6 2-aminochalcone 
• 108-24-7 acetic anhydride 
• 100-52-7 benzaldehyde 
• 5234-26-4 N-(2-acetylphenyl)acetamide 
• 19591-17-4 o-iodoacetanilide 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 551-93-9 2-aminoacetophenone 
• 14371-10-9 (E)-3-phenylpropenal 
• 103-84-4 Acetanilid 
• 62-53-3 aniline 
• 577-59-3 2-acetylnitrobenzene 
• 75-36-5 acetyl chloride 

Downstream Products

• 124890-66-0 1-(2-Aminophenyl)-2-bromo-3-ethoxy-3-phenyl-1-propanone 
• 124857-08-5 1-(2-Aminophenyl)-2-bromo-3-ethoxy-3-phenyl-1-propanone 
• 124857-06-3 (Z)-2'-Acetamido-α-bromochalcone 
• 124857-05-2 (E)-2'-Acetamido-α-bromochalcone 
• 124856-98-0 1-<2-(benzenesulfonamide)phenyl>-2-bromo-3-methoxy-3-phenyl-1-propanone 
• 124857-04-1 cis-1-(Phenylsulfonyl)-3-bromo-1,2,3,4-tetrahydro-2-phenyl-4-quinolone 
• 124857-07-4 cis-1-Acetyl-3-bromo-1,2,3,4-tetrahydro-2-phenyl-4-quinolone 
• 124856-97-9 1-(2-Aminophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone 
• 124856-94-6 2'-Aminochalcone Dibromide 
• 124857-09-6 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone 
• 60355-89-7 4-Acetoxy-1-acetyl-1,2-dihydro-2-phenylquinoline 
• 14802-18-7 2-phenyl-1H-quinolin-4-one 
• 136490-99-8 erythro-2-hydroxy-3-methoxy-1-(2'-acetamidophenyl)-3-phenylpropan-1-one 
• 136491-02-6 threo-1-(2'-acetamidobenzoyl)-2-phenylethylene chlorohydrin 

Relevant articles and documents

Synthesis of [1,4]Thiazino[4,3- a]indol-10-one Derivatives through Radical Anti Aza-Michael Addition of 2′-Aminochalcones

An efficient method for the synthesis of [1,4]thiazino[4,3-a]indole derivatives using sodium chlorodifluoroacetate (ClCF2CO2Na) and elemental sulfur as the difluoromethylthiolating reagent system has been developed. Three-component reactions of 2′-aminochalcones, sulfur, and ClCF2CO2Na under basic conditions using TEMPO as the oxidant afforded [1,4]thiazino[4,3-a]indol-10-ones containing a difluoromethyl thioether moiety in good yields. Four bonds including one C-N, two C-S, and one C-C bonds are selectively formed in the sequential transformation process.

Aza analogs of flavones as potential antimicrobial agents

In search for the new antimicrobial agents owing to drug resistant bacteria and fungi, a series of rationally designed aza analogs of flavones has been designed and synthesized. The design of the analogs involved incorporation of quinolone nucleus within

Palladium-catalyzed heteroannulation with acetylenic carbinols as synthons-synthesis of quinolines and 2,3-dihydro-4(1H)-quinolones

o-Iodoanilides 4 reacted with terminal acetylenic carbinols 5 under palladium-catalyzed conditions to yield o-substituted anilides 6. Most of the anilides 6 could be cyclized with NaOEt/EtOH to 2-arylquinolines 2. o-Iodoanilines 7 reacted with carbinols 5 leading to 8 which on palladium(II) assisted cyclisation afforded substituted quinolines 2. An excellent synthesis of the alkaloid dubamine (2n) is reported. Also, the anilides 6 on acid-catalyzed rearrangement, deprotection and cyclisation led to the 2-aryl-2, 3-dihydro-4(1H)-quinolones 16.