131575-15-0

Basic information

• Product Name: 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one
• Synonyms: 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one
• CAS NO: 131575-15-0
• Molecular Weight: 403.478
• Mol File: 131575-15-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one(131575-15-0)
• EPA Substance Registry System: 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one(131575-15-0)

Safety Data

• Hazardous Substances Data: 131575-15-0(Hazardous Substances Data)

Upstream product

• 848489-79-2 (4R,7aR,12bS)-9-(benzyloxy)-7-methoxy-3-methyl-2,3,4,7a-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline 
• 41135-98-2 14-hydroxymorphinone 
• 467-04-9 oripavine 
• 26988-26-1 3-O-benzyl-14-hydroxymorphinone 
• 77-78-1 dimethyl sulfate 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 38252-24-3 14-O-methylcodeinone 
• 124942-33-2 (-)-7,8-didehydro-4,5α-epoxy-3-hydroxy-14-methoxy-N-methylmorphinan-6-one hydrobromide 

Downstream Products

• 131575-18-3 3-(Benzyloxy)-17-(cyclopropylmethyl)-7,8-didehydro-4,5α-epoxy-14β-methoxymorphinan-6-one 
• 131575-17-2 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxymorphinan-6-one 

Relevant articles and documents

PROCESSES FOR THE PRODUCTION OF 14 - OXYGENATED MORPHINAN - 6 - ONES

A process for the production of a 14-oxygenated morphinan-6-one of formula (I) wherein R1 is alkyl, alkenyl, alkynyl, cycloalkylalkyl, aralkyl, R3 is hydrogen, and R4 is hydrogen, wherein oripavine, 14-hydroxymorphinone or oxymorphone is used as starting material.

160. Synthesis and Biological Evaluation of 14-Alkoxymorphinans - Part 7 - 14,14'-Dimethoxy Analogues of Norbinaltorphimine: Synthesis and Determination of Their χ Opioid Antagonist Selectivity

The bimorphinans 6 and 7 have been prepared from 14-O-methylnaloxone (2) and 14-O-methylnaltrexone (3), respectively.The known compounds 2 and 3 were synthesized by a different route than the route described.Bimorphinan 7 possessed a similar ξ receptor af