41135-98-2

Basic information

• Product Name: 14-hydroxymorphine-6-one
• Synonyms: 14-hydroxymorphine-6-one;(5R)-3,14-Dihydroxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-one;(5α)-7,8-Didehydro-4α,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one;OxyMorphinone
• CAS NO: 41135-98-2
• Molecular Formula: C₁₇H₁₇NO₄
• Molecular Weight: 317.33646
• EINECS: 255-236-9
• Mol File: 41135-98-2.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 14-hydroxymorphine-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 14-hydroxymorphine-6-one(41135-98-2)
• EPA Substance Registry System: 14-hydroxymorphine-6-one(41135-98-2)

Safety Data

• Hazardous Substances Data: 41135-98-2(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

Oxymorphinone is a major metabolite of Morphine (M652290).

Upstream product

• 109440-85-9 4,5α-epoxy-3,8β,14-trihydroxy-17-methyl-morphinan-6-one 
• 508-54-3 14-hydroxycodeinone 
• 467-04-9 oripavine 
• 57-27-2 MORPHIN 
• 115-37-7 thebaine 
• 23185-97-9 8β,14-dihydroxy-7,8-dihydrocodeinone 
• 1234788-73-8 oxymorphinone-N-oxide hydrochloride 

Downstream Products

• 3371-56-0 6α-oxymorphol 
• 862190-33-8 6-O-tosyl-14-hydroxy-3-deoxymorphine 
• 84116-46-1 7,8-didehydro-4,5α-epoxymorphinan-6-keto-3,14-diol 
• 76-41-5 oxymorphone 
• 465-65-6 Naloxone 
• 33522-95-1 noroxymorphone 
• 26988-26-1 3-O-benzyl-14-hydroxymorphinone 
• 1357076-49-3 3-O-benzyl-14-O-but-2-enyloxymorphinone 
• 131575-15-0 3-(Benzyloxy)-7,8-didehydro-4,5α-epoxy-14β-methoxy-17-methylmorphinan-6-one 
• 16590-41-3 Naltrexone 
• 20594-83-6 nalbuphine 
• 64643-76-1 4,5α-epoxy-3,14-diacetoxy-6-oxo-17-methylmorphinan 

Relevant articles and documents

Direct and simple O-demethylation of thebaine to oripavine

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PROCESS FOR OBTAINING 3,14-DIACETYLOXYMORPHONE FROM ORIPAVINE

The present invention relates to a new process for obtaining 3,14-diacetyloxymorphone from oripavine, a process to transform the obtained 3,14-diacetyloxymorphone into a noroxymorphone and a process to transform said noroxymorphone into naloxone, naltrexone, nalbuphine, nalfurafine or nalmefene.

PROCESS FOR IMPROVED OXYMORPHONE SYNTHESIS

Processes for preparing oxymorphone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxymorphinone salt in the presence of trifluoroacetic acid and/or a glycol.