84116-46-1 Usage
Description
(5alpha)-7,8-Didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one, commonly known as oxymorphone, is a semi-synthetic opioid analgesic medication derived from morphine. It is characterized by its potent pain-relieving properties and is used to treat moderate to severe pain. Oxymorphone exerts its effects by binding to the opioid receptors in the brain and spinal cord, effectively blocking the sensation of pain. It is recognized for its higher potency compared to morphine and is often prescribed to patients who do not respond well to other opioid medications. However, it also carries a significant risk of addiction, necessitating cautious use and the supervision of a healthcare professional. Common side effects associated with oxymorphone use include dizziness, drowsiness, nausea, constipation, and headache.
Uses
Used in Pharmaceutical Industry:
Oxymorphone is used as an analgesic agent for the treatment of moderate to severe pain. Its high potency and effectiveness in patients who do not respond well to other opioids make it a valuable option in pain management. However, due to its potential for addiction, it is crucial to administer oxymorphone under strict medical supervision and with careful monitoring of the patient's condition.
Used in Pain Management:
Oxymorphone serves as a potent pain-relieving medication, particularly for patients who have not found relief with other opioid medications. Its ability to bind to opioid receptors in the brain and spinal cord helps to block the sensation of pain, providing significant relief to those suffering from moderate to severe pain. The use of oxymorphone in pain management is subject to careful consideration of the patient's medical history, the severity of their pain, and the potential risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 84116-46-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,1,1 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 84116-46:
(7*8)+(6*4)+(5*1)+(4*1)+(3*6)+(2*4)+(1*6)=121
121 % 10 = 1
So 84116-46-1 is a valid CAS Registry Number.
84116-46-1Relevant articles and documents
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Fishman,J. et al.
, p. 556 - 557 (1973)
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SYNTHESIS OF NOROXYMORPHONE
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Page/Page column 6; 7; 26, (2019/06/23)
The present invention relates to the improved synthesis of noroxymorphone of formula (III). Particularly, the invention shows a way how to reduce the impurity level in the product avoiding lengthy purification steps.
PROCESSES AND OXAZOLIDINE-CONTAINING INTERMEDIATES FOR THE PREPARATION OF MORPHINE ANALOGS AND DERIVATIVES
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Paragraph 00277-00281, (2017/11/15)
The present invention relates to processes useful in the preparation of morphine analogs and derivatives, such as naltrexone, naloxone and nalbuphine and intermediates in the synthesis of said morphine analogs and derivatives. In a particular example, the process begins with for example oxymorphone, oxycodone, 14-hydroxycodeinone or 14- hydroxymorphinone, and includes the formation of an oxazolidine-containing intermediate using catalytic oxidation.
