131669-68-6

Basic information

• Product Name: (2S,3S)-3-Benzyl-1-(2,2-dimethyl-propionyl)-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 131669-68-6
• Molecular Weight: 303.401
• Mol File: 131669-68-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-Benzyl-1-(2,2-dimethyl-propionyl)-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-Benzyl-1-(2,2-dimethyl-propionyl)-pyrrolidine-2-carboxylic acid methyl ester(131669-68-6)
• EPA Substance Registry System: (2S,3S)-3-Benzyl-1-(2,2-dimethyl-propionyl)-pyrrolidine-2-carboxylic acid methyl ester(131669-68-6)

Safety Data

• Hazardous Substances Data: 131669-68-6(Hazardous Substances Data)

Upstream product

• 131669-63-1 2-(3-Benzyl-N-pivaloylpyrrolidin-2-ylidene)-1,3-dithiane 
• 131669-61-9 2-<1-(2,2-dimethylpropanoyl)pyrrolidin-2-ylidene>-1,3-dithiane 
• 75041-78-0 N-pivaloyl proline 
• 3282-30-2 pivaloyl chloride 
• 127811-84-1 2-(4-azidobut-1-ylidene)-1,3-dithiane 
• 3315-60-4 methanolate 
• 131669-28-8 (2S,3S)-3-Benzyl-1-(2,2-dimethyl-propionyl)-pyrrolidine-2-carbothioic acid S-(3-mercapto-propyl) ester 

Downstream Products

• 131669-72-2 (+/-)-3-Benzylproline 

Relevant articles and documents

Generation of α-amino acid homoenolate equivalents. Synthesis of 3-substituted prolines

Deprotonation of the N-protected aminoketene-S,S-acetal (6) and reaction of allylic anion (7) with electrophiles leads to adducts (8) which have been converted to 3-substituted prolines (11). Conformationally constrained variants (11d) and (11e) of aspartic and glutamic acid have been prepared.