131899-85-9

Basic information

• Product Name: 2,6-di-t-butyl-4-methylphenyl cis-(1R,2S)-2-phenylcyclopropane-1-carboxylate
• Synonyms: 2,6-di-t-butyl-4-methylphenyl cis-(1R,2S)-2-phenylcyclopropane-1-carboxylate
• CAS NO: 131899-85-9
• Molecular Weight: 364.528
• Mol File: 131899-85-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,6-di-t-butyl-4-methylphenyl cis-(1R,2S)-2-phenylcyclopropane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-di-t-butyl-4-methylphenyl cis-(1R,2S)-2-phenylcyclopropane-1-carboxylate(131899-85-9)
• EPA Substance Registry System: 2,6-di-t-butyl-4-methylphenyl cis-(1R,2S)-2-phenylcyclopropane-1-carboxylate(131899-85-9)

Safety Data

• Hazardous Substances Data: 131899-85-9(Hazardous Substances Data)

Upstream product

• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 100-42-5 styrene 
• 125640-92-8 2,6-di-tert-butyl-4-methylphenyl diazoacetate 
• 125641-00-1 2,6-Bis(1,1-dimethylethyl)-4-methylphenyl 2-diazo-3-butenoate 

Relevant articles and documents

Chiral C2-symmetric bisferrocenyldiamines as ligands for transition metal catalyzed asymmetric cyclopropanation and aziridination

A new series of chiral C2-symmetric bisferrocenyldiimine 1 and bisferrocenyldiamines 2 and 3 proved to be efficient ligands for the copper(I)-catalyzed asymmetric cyclopropanation, cyclopropenation, and aziridination of alkenes and alkynes to give high diastereo- and enantioselectivity as well as high chemical yields. In some instances the enantiomeric excesses of cyclopropanated products are among the highest (>97% ee) ever reported. Comparative studies show that stereoselectivity depends highly on the steric variation both in the ligand and the substrate. Other transition metal complexes incorporating some of these ligands such as Ru(3c)Cl2, [(NBD)Rh(2)]ClO4, [Cu(2)(MeCN)2]PF6, and Pd(2)Cl2 also demonstrated high enantioselectivity in cyclopropanation reactions.

Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions

Exceptionally high trans (anti) stereoselectivities are obtained in rhodium(II) carboxylate and carboxamide catalyzed alkene cyclopropanation reactions with 2,6-di-tert-butyl-4-methylphenyl diazoacetate (BDA). With monosubstituted ethylenes, use of rhodiu