132195-48-3

Basic information

• Product Name: 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester
• Synonyms: 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester
• CAS NO: 132195-48-3
• Molecular Weight: 428.438
• Mol File: 132195-48-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester(132195-48-3)
• EPA Substance Registry System: 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester(132195-48-3)

Safety Data

• Hazardous Substances Data: 132195-48-3(Hazardous Substances Data)

Upstream product

• 132195-43-8 3-(2,6-dichloro-3-fluoro-4-methyl-5-pyridinyl)-3-oxopropionic acid ethyl ester 
• 149366-73-4 2,6-Dichloro-5-fluoro-4-methyl-nicotinoyl chloride 
• 132195-42-7 2,6-dichloro-5-fluoro-4-methylnicotinic Acid 
• 82671-06-5 2,6-dichloro-5-fluoro-3-pyridinecarboxylic acid 
• 371-40-4 4-fluoroaniline 
• 132195-46-1 (Z)-2-(2,6-Dichloro-5-fluoro-4-methyl-pyridine-3-carbonyl)-3-(4-fluoro-phenylamino)-acrylic acid ethyl ester 
• 132195-45-0 2-(ethoxymethylene)-3-(2,6-dichloro-3-fluoro-4-methyl-5-pyridinyl)-3-oxopropionic acid ethyl ester 
• 103831-11-4 (S)-3-aminopyrrolidine dihydrochloride 
• 79286-79-6 (3S)-3-aminopyrrolidine 

Downstream Products

• 132195-69-8 7-<(3S)-3-amino-1-pyrrolidynyl>-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 

Relevant articles and documents

SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL N-1-ARYL-6-FLUORO-5-METHYL-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS

A series of 5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids was prepared in which the N-1 position was substituted by various aryl groups.Seven compounds showed excellent in vitro antibacterial activity against Gram-positive and Gram-negative strains.