132283-76-2

Basic information

• Product Name: (1S,1'R)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-2-(2-hydroxy-1-phenylethyl)-1,2,3,4-tetrahydroisoquinoline
• Synonyms: (1S,1'R)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-2-(2-hydroxy-1-phenylethyl)-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 132283-76-2
• Molecular Weight: 449.547
• Mol File: 132283-76-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,1'R)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-2-(2-hydroxy-1-phenylethyl)-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,1'R)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-2-(2-hydroxy-1-phenylethyl)-1,2,3,4-tetrahydroisoquinoline(132283-76-2)
• EPA Substance Registry System: (1S,1'R)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-2-(2-hydroxy-1-phenylethyl)-1,2,3,4-tetrahydroisoquinoline(132283-76-2)

Safety Data

• Hazardous Substances Data: 132283-76-2(Hazardous Substances Data)

Upstream product

• 2859-78-1 4-Bromoveratrole 
• 56613-80-0 D-2-phenylglycinol 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 123285-94-9 (3R,10bS)-8,9-dimethoxy-3-phenyl-2,3,5,6-tetrahydro-10bH-oxazolo<2.3-a>isoquinoline 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 132283-67-1 6,7-dimethoxy-1-ethoxyisochroman 
• 132283-68-2 2-(2-chloroethyl)-4,5-dimethoxybenzaldehyde 

Downstream Products

• 33770-43-3 (S)-1-1-(3',4'-dimethoxylphenyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 

Relevant articles and documents

An efficient method for construction of tetrahydroisoquinoline skeleton via double cyclization process using ortho-vinylbenzaldehydes and amino alcohols: application to the synthesis of (S)-cryptostyline II

Thermal double cyclization reaction using ortho-vinylbenzaldehyde and 3-aminopropanols proceeded smoothly to give isoquinoline derivatives via 6π-azaelectrocyclization pathway. The method was applied to the efficient synthesis of (S)-cryptostyline II.