132382-46-8

Basic information

• Product Name: methyl (E)-11-<ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate
• Synonyms: methyl (E)-11-<ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate
• CAS NO: 132382-46-8
• Molecular Weight: 440.499
• Mol File: 132382-46-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (E)-11-<ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-11-<ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate(132382-46-8)
• EPA Substance Registry System: methyl (E)-11-<ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate(132382-46-8)

Safety Data

• Hazardous Substances Data: 132382-46-8(Hazardous Substances Data)

Upstream product

• 132382-43-5 2-amino-4,5-dimethylformanilide 
• 132637-23-1 methyl 11-formylmethylene-6,11-dihydrodibenzoxepin-2-carboxylate 
• 113836-33-2 2-<(4-methoxycarbonyl)phenoxymethyl>benzoic acid 
• 171182-96-0 4,5-dimethyl-2-nitroformanilide 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 95-64-7 4-amino-o-xylene 
• 79669-87-7 methyl 11-oxo-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate 
• 79670-12-5 methyl 11-methylene-6,11-dihydrodibenz-[b,e]oxepin-2-carboxylate 
• 2198-54-1 N-(3,4-dimethylphenyl)acetamide 
• 6972-71-0 4,5-dimethyl-2-nitrobenzenamine 
• 6970-77-0 N-(4,5-dimethyl-2-nitrophenyl)acetamide 
• 87-41-2 2-benzofuran-1(3H)-one 
• 132382-46-8 11-[2-[(E)-2-Formylamino-4,5-dimethyl-phenylimino]-eth-(E)-ylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester 

Downstream Products

• 132382-46-8 11-[2-[(E)-2-Formylamino-4,5-dimethyl-phenylimino]-eth-(E)-ylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester 
• 127166-41-0 sodium (E)-11-<2-(5,6-dimethyl-1-benzimidazolyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate monohydrate 

Relevant articles and documents

Improved synthesis of thromboxane A2 receptor antagonists with a dibenzoxepin ring system

Two derivatives of sodium (E)-11-[2-(1-benzimidazolyl)ethylidene]11-oxo-6,11-dihydrodibenz[b,e]o xepin-2-carboxylate, novel nonprostanoid thromboxane A2 (TXA2) receptor antagonists, were synthesized from methyl 11-oxo-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate. The carbonyl group at C11 was converted into a formylmethylene, then into a 1-azadiene moiety by reaction with a 2-aminoformanilide derivative. Stereo- and regioselective elaboration of the unsymmetrical imidazoles was achieved through a sequence of the transformation of E,Z-1-azadiene intermediates to E isomers under acidic conditions followed by cyclization to imidazoles.