13298-50-5

Basic information

• Product Name: 1-naphthalen-2-ylbutane-1,3-dione
• Synonyms: 1-naphthalen-2-ylbutane-1,3-dione
• CAS NO: 13298-50-5
• Molecular Formula: C₁₄H₁₂O₂
• Molecular Weight: 212.24
• Mol File: 13298-50-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 369.7°Cat760mmHg
• Flash Point: 138.7°C
• Appearance: /
• Density: 1.145g/cm³
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: 1-naphthalen-2-ylbutane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-naphthalen-2-ylbutane-1,3-dione(13298-50-5)
• EPA Substance Registry System: 1-naphthalen-2-ylbutane-1,3-dione(13298-50-5)

Safety Data

• Hazardous Substances Data: 13298-50-5(Hazardous Substances Data)

Usage

Appearance

Yellow crystalline solid

Usage

Reagent in organic synthesis, building block for pharmaceuticals and dyes, fragrance ingredient in perfumes, flavoring agent in food products

Chemical structure

Naphthalene ring, butane chain, ketone group

Reactivity

Unique due to the presence of the ketone group

Potential applications

Medicinal chemistry due to structural features and biological activities

InChI:InChI=1/C14H12O2/c1-10(15)8-14(16)13-7-6-11-4-2-3-5-12(11)9-13/h2-7,9H,8H2,1H3

Upstream product

• 141-78-6 ethyl acetate 
• 93-08-3 methyl 2-naphthyl ketone 
• 57647-89-9 isopropenyl 2-naphthoate 
• 108-24-7 acetic anhydride 
• 201230-82-2 carbon monoxide 
• 612-55-5 2-iodonaphthalene 
• 67-64-1 acetone 
• 79-20-9 acetic acid methyl ester 

Downstream Products

• 124435-10-5 1-methyl-3-(2-naphthyl)-2-(p-sulphamylbenzeneazo)propane-1,3-dione 
• 124435-12-7 4-[1-(Naphthalene-2-carbonyl)-2-oxo-propylazo]-N-pyrimidin-2-yl-benzenesulfonamide 
• 124435-17-2 N-(3-Methyl-[1,2,4]thiadiazol-5-yl)-4-[1-(naphthalene-2-carbonyl)-2-oxo-propylazo]-benzenesulfonamide 
• 124435-13-8 N-(2,6-Dimethyl-pyrimidin-4-yl)-4-[1-(naphthalene-2-carbonyl)-2-oxo-propylazo]-benzenesulfonamide 
• 124435-15-0 N-(4,6-Dimethoxy-pyrimidin-2-yl)-4-[1-(naphthalene-2-carbonyl)-2-oxo-propylazo]-benzenesulfonamide 
• 124435-14-9 N-(4,6-Dimethyl-pyrimidin-2-yl)-4-[1-(naphthalene-2-carbonyl)-2-oxo-propylazo]-benzenesulfonamide 
• 93-08-3 methyl 2-naphthyl ketone 
• 93-09-4 naphthalene-2-carboxylate 
• 124435-18-3 3-methyl-1-(4-methylphenyl)-5-(2-naphthyl)-4-(p-sulphamylbenzeneazo)pyrazole 
• 124435-24-1 4-[3-Methyl-5-naphthalen-2-yl-1-(1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-1H-pyrazol-4-ylazo]-benzenesulfonamide 
• 13298-86-7 1--butan-1,2,3-trion-2-triphenylphosphazin 
• 1232578-70-9 ethyl 4-(2-(naphthalen-2-yl)-2-oxoethyl)benzoate 
• 1210068-80-6 C₂₆H₂₂O₉ 
• 1210068-93-1 C₂₆H₂₂O₉ 

Relevant articles and documents

Multi-stimuli-responsive fluorescence of axially chiral 4-ene-β-Diketones

A unique series of simple, smart, and chiral binaphthalene-substituted 4-ene-β-diketones molecules has been designed and prepared. Their optical properties, charge contribution, and transition process highly depend on their chemical structures. These π-conjugated materials are highly emissive in both solution and solid (emission quantum yield up to 68%), owing to the inhibition of enol-keto tautomerization and the effect of steric hindrance from binaphthalene. Through ethylenic bond hydrolysis, they can be used for not only cation/anion sensing but also chiral amino acids recognition. Moreover, at low concentrations, they have little cytotoxicity to living cells and can stain cytoplasm. Therefore, they afford a new platform in the design of multi-stimuli-responsive, smart, and chiral materials.

I2-Promoted [3+2] Cyclization of 1,3-Diketones with Potassium Thiocyanate: a Route to Thiazol-2(3H)-One Derivatives

An I2-promoted strategy has been developed for the synthesis of thiazol-2(3H)-one derivatives from 1,3-diketones with potassium thiocyanate. This [3+2] cyclization reaction involves C?S and C?N bond formation and exhibits good functional group tolerance. A series of thiazol-2(3H)-one derivatives are obtained in moderate to good yields. (Figure presented.).

Direct synthesis of 2,3,5-trisubstituted pyrroles: via copper-mediated one-pot multicomponent reaction

We have developed a copper-mediated one-pot synthesis of 2,3,5-trisubstituted pyrroles from 1,3-dicarbonyl compounds and acrylates using ammonium acetate as a nitrogen source. The reaction achieves C-C and C-N bond formation and provides an efficient approach to access highly functionalized pyrroles without further raw material preparation. This method is operationally simple, compatible with a wide range of functional groups, and provides the target products in moderate to good yields. This journal is