1333257-45-6

Basic information

• Product Name: 5-chloro-6-(3-fluorobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile
• Synonyms: 5-chloro-6-(3-fluorobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile
• CAS NO: 1333257-45-6
• Molecular Weight: 302.695
• Mol File: 1333257-45-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-chloro-6-(3-fluorobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-6-(3-fluorobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile(1333257-45-6)
• EPA Substance Registry System: 5-chloro-6-(3-fluorobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile(1333257-45-6)

Safety Data

• Hazardous Substances Data: 1333257-45-6(Hazardous Substances Data)

Upstream product

• 59223-73-3 diethyl 2-(3-fluorobenzyl)malonate 
• 1333257-58-1 6-(3-fluorobenzyl)-5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carbonitrile 
• 1333257-57-0 6-(3-fluorobenzyl)-5,7-dihydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile 

Relevant articles and documents

HERBICIDAL AZOLOPYRIMIDINES

The present invention relates to azolopyrimidines of formula (I) wherein the variables are defined according to the description, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants and a method for controlling unw

Inhibitors of the herbicidal target IspD: Allosteric site binding

The pick of the pockets: The first inhibitors for IspD, an enzyme from the non-mevalonate pathway of isoprenoid biosynthesis, are described. High-throughput-screening revealed a hit with an IC50 value of 140 nM. Co-crystal structure analyses of the binding mode in the newly formed allosteric pocket (see structure, red ball: water O atom), lead to the synthesis of a set of 17 derivatives which were tested to optimize the herbicidal activity.