1334313-47-1

Basic information

• Product Name: (Z)-methyl 2-phenyl-2-(2-tosylhydrazono)acetate
• Synonyms: (Z)-methyl 2-phenyl-2-(2-tosylhydrazono)acetate
• CAS NO: 1334313-47-1
• Molecular Weight: 332.38
• Mol File: 1334313-47-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-methyl 2-phenyl-2-(2-tosylhydrazono)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-methyl 2-phenyl-2-(2-tosylhydrazono)acetate(1334313-47-1)
• EPA Substance Registry System: (Z)-methyl 2-phenyl-2-(2-tosylhydrazono)acetate(1334313-47-1)

Safety Data

• Hazardous Substances Data: 1334313-47-1(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 3558-61-0 methyl 2-methoxy-2-phenylacetate 
• 22979-35-7 Methyl phenyldiazoacetate 
• 64464-76-2 methyl 2-phenyl-2-(phenylamino)acetate 
• 169512-94-1 (+/-)-N-tert-butoxycarbonyl-α-phenylglycine methyl ester 

Relevant articles and documents

Synthesis of substituted 1 H-indazoles from arynes and hydrazones

The 1H-indazole skeleton can be constructed by a [3 + 2] annulation approach from arynes and hydrazones. Under different reaction conditions, both N-tosylhydrazones and N-aryl/alkylhydrazones can be used to afford a variety of indazoles. The former reaction affords 3-substituted indazoles either via in situ generated diazo compounds or through an annulation/elimination process. The latter reaction leads to 1,3-disubstituted indazoles likely through an annulation/oxidation process. The reactions operate under mild conditions and can accommodate aryl, vinyl, and less satisfactorily, alkyl groups.