133565-97-6

Basic information

• Product Name: 1-(1-phenylethenyl)benzocyclobuten-1-ol
• Synonyms: 1-(1-phenylethenyl)benzocyclobuten-1-ol
• CAS NO: 133565-97-6
• Molecular Weight: 222.287
• Mol File: 133565-97-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(1-phenylethenyl)benzocyclobuten-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-phenylethenyl)benzocyclobuten-1-ol(133565-97-6)
• EPA Substance Registry System: 1-(1-phenylethenyl)benzocyclobuten-1-ol(133565-97-6)

Safety Data

• Hazardous Substances Data: 133565-97-6(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 3469-06-5 benzocyclobutenone 
• 76886-55-0 Acetophenone 2,4,6-triisopropylbenzenesulphonyl hydrazone 
• 67300-99-6 1-phenylethenylmagnesium bromide 

Downstream Products

• 175026-12-7 1-(2-methylphenyl)-2-phenylprop-2-en-1-one 
• 7498-87-5 2-phenyl-3,4-dihydro-2H-naphthalen-1-one 

Relevant articles and documents

RhI-catalyzed benzo/[7+1] cycloaddition of cyclopropyl-benzocyclobutenes and CO by merging thermal and metal-catalyzed C-C bond cleavages

A Rh-catalyzed benzo/[7+1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to benzocyclooctenones has been developed. In this reaction, CP-BCB acts as a benzo/7-C synthon and the reaction involves two C-C bond cleavages: a thermal electrocyclic ring-opening of the four-membered ring in CP-BCB and a Rh-catalyzed C-C cleavage of the cyclopropane ring.

The preparation of α-tetralones from benzocyclobutenones via sequential thermal electrocyclic reactions

1-Alkenylbenzocyclobuten-1-ols, prepared from benzocyclobutenones via the addition of alkenylmagnesium bromides, or the addition of alkynyllithium reagents followed by (E)-selective reduction of the triple bond, undergo successive thermal 4π and 6π electrocyclic reactions leading to substituted 3,4-dihydro-1(2H)-naphthalenones.