7498-87-5

Basic information

• Product Name: 2-Phenyl-3,4-dihydro-1(2H)-naphthalenone
• Synonyms: 2-Phenyl-1,2,3,4-tetrahydronaphthalene-1-one;2-Phenyl-3,4-dihydro-1(2H)-naphthalenone;2-Phenyltetralin-1-one;3,4-Dihydro-2-phenylnaphthalen-1(2H)-one
• CAS NO: 7498-87-5
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 0
• Mol File: 7498-87-5.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 374.7°C at 760 mmHg
• Flash Point: 164.2°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 8.19E-06mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 2-Phenyl-3,4-dihydro-1(2H)-naphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-3,4-dihydro-1(2H)-naphthalenone(7498-87-5)
• EPA Substance Registry System: 2-Phenyl-3,4-dihydro-1(2H)-naphthalenone(7498-87-5)

Safety Data

• Hazardous Substances Data: 7498-87-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H14O/c17-16-14-9-5-4-8-13(14)10-11-15(16)12-6-2-1-3-7-12/h1-9,15H,10-11H2

Upstream product

• 17215-80-4 2-chloro-1-tetralone 
• 2901-34-0 2,4-diphenylbutanoic acid 
• 21460-77-5 2,4-diphenyl-butyryl chloride 
• 133565-97-6 1-(1-phenylethenyl)benzocyclobuten-1-ol 
• 109327-32-4 c-2-chloro-1,2,3,4-tetrahydro-1-phenylnaphthalen-r-1-ol 
• 86738-87-6 2-phenyl-2-phenylthio-1-tetralone 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 108-90-7 chlorobenzene 
• 38858-72-9 1-trimethylsiloxy-3,4-dihydronaphthalene 
• 108-86-1 bromobenzene 
• 20669-52-7 3-phenyl-1,2-dihydronaphthalene 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 3469-06-5 benzocyclobutenone 
• 67300-99-6 1-phenylethenylmagnesium bromide 

Downstream Products

• 856082-35-4 1-ethyl-2-phenyl-1,2,3,4-tetrahydro-[1]naphthol 
• 861049-95-8 1-Hydroxy-1.2-diphenyl-1.2.3.4-tetrahydro-naphthalin 
• 858439-03-9 (2-phenyl-3,4-dihydro-[1]naphthyl)-acetic acid 
• 109246-61-9 4-ethyl-3-phenyl-1,2-dihydro-naphthalene 
• 1022-15-7 4-methyl-3-phenyl-1,2-dihydronaphthalene 
• 94540-42-8 (±)-2-methyl-2-phenyl-3,4-dihydronaphthalin-1(2H)-one 
• 109327-50-6 1,2-dihydro-3-phenyl-4-vinylnaphthalene 
• 7351-86-2 (1R,2R)-2-Phenyl-1-vinyl-1,2,3,4-tetrahydro-naphthalen-1-ol 
• 7351-86-2 (1R,2S)-2-Phenyl-1-vinyl-1,2,3,4-tetrahydro-naphthalen-1-ol 
• 73316-11-7 C₁₈H₁₆N₂O₂ 
• 20495-17-4 2-phenyl-1-tetralone oxime 
• 10048-83-6 1-<4-(2-Diaethylamino-aethoxy)-phenyl>-2-phenyl-1-hydroxy-1,2,3,4-tetrahydro-naphthalin 
• 881851-79-2 (1S,2R)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 28717-84-2 7-chloro-3-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 

Relevant articles and documents

Base-controlled chemoselectivity: direct coupling of alcohols and acetonitriles to synthesise α-alkylated arylacetonitriles or acetamides

We achieved chemoselective synthesis of α-alkylated arylacetonitriles and acetamides by combining Ir complex-catalysed direct coupling of alcohols and nitriles by a simple adjustment of the base. Methanol and ethanol performed well as the alkylating reagents. This method of acetonitrile alkylation provided a novel approach for carbon chain extension.

Oxidation of Nonactivated Anilines to Generate N-Aryl Nitrenoids

A low-temperature, protecting-group-free oxidation of 2-substituted anilines has been developed to generate an electrophilic N-aryl nitrenoid intermediate that can engage in C-NAr bond formation to construct functionalized N-heterocycles. The exposure of 2-substituted anilines to PIFA and trifluoroacetic acid or 10 mol percent Sc(OTf)3 triggers nitrenoid formation, followed by productive and selective C-NAr and C-C bond formation to yield spirocyclic- or bicyclic 3H-indoles or benzazepinones. Our experiments demonstrate the breadth of these oxidative processes, uncover underlying fundamental elements that control selectivity, and demonstrate how the distinct reactivity patterns embedded in N-aryl nitrenoid reactive intermediates can enable access to functionalized 3H-indoles or benzazepinones.

Blue Light Promoted Difluoroalkylation of Aryl Ketones: Synthesis of Quaternary Alkyl Difluorides and Tetrasubstituted Monofluoroalkenes

A facile and cost-effective method for the preparation of fluoroalkylated compounds has been described by the direct photoexcitation of halofluoroalkanes with blue light absorptivity, enabling the difluoroalkylation of aryl ketones. The methodology has provided an efficient, mild, and catalyst-free synthetic method for quaternary difluoroalkylated arenes and tetrasubstituted monofluoroalkenes.