2901-34-0

Basic information

• Product Name: Benzenebutanoic acid, a-phenyl-
• Synonyms: Benzenebutanoic acid, α-phenyl-
• CAS NO: 2901-34-0
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 2901-34-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 110 °C
• Boiling Point: 190 °C(Press: 1 Torr)
• Density: 1.137±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenebutanoic acid, a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, a-phenyl-(2901-34-0)
• EPA Substance Registry System: Benzenebutanoic acid, a-phenyl-(2901-34-0)

Safety Data

• Hazardous Substances Data: 2901-34-0(Hazardous Substances Data)

Upstream product

• 28744-77-6 sodium diethyl-2-phenylmalonate 
• 103-63-9 1-phenyl-2-bromoethane 
• 6268-00-4 4-oxo-2,4-diphenylbutanenitrile 
• 53608-81-4 2,4-diphenyl-butyric acid ethyl ester 
• 10034-85-2 hydrogen iodide 
• 64-19-7 acetic acid 
• 101-97-3 Ethyl 2-phenylethanoate 
• 140-29-4 phenylacetonitrile 
• 21034-29-7 2,4-diphenyl-γ-butyrolactone 
• 5558-42-9 rac-2,4-diphenylbutyronitrile 
• 20985-27-7 2,4-diphenylbutanamide 
• 492-38-6 2-phenylacrylic acid 
• 401636-52-0 di-tert-butyl 4-benzyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 7498-87-5 2-phenyl-3,4-dihydro-2H-naphthalen-1-one 
• 77985-15-0 2,4-Diphenyl-buttersaeure-<2-diaethylamino-aethylester> 
• 2901-34-0 2,4-diphenyl-butyric acid 
• 137074-16-9 1-(2,4-Diphenylbutanoyl)-4-(pyridin-3-ylcyanomethyl)piperazine 
• 21460-77-5 2,4-diphenyl-butyryl chloride 
• 2902-58-1 2-Methyl-2,4-diphenyl-buttersaeure 
• 861049-95-8 1-Hydroxy-1.2-diphenyl-1.2.3.4-tetrahydro-naphthalin 
• 30877-08-8 1,2-diphenylnaphthalene 
• 57652-90-1 3,4-diphenyl-1,2-dihydronaphthalene 
• 111027-00-0 7-bromo-3-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 20495-17-4 2-phenyl-1-tetralone oxime 
• 3300-62-7 3-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 28717-84-2 7-chloro-3-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 

Relevant articles and documents

Aggregation and alkylation of enolates of 2-phenyl-α-tetralone and 2,6-diphenyl-α-tetralone

The cesium (1-Cs, CsPhPAT) and lithium (1-Li, LiPhPAT) enolates of 2,6-diphenyl-α-tetralone, 1, and the lithium enolate (2-Li, LiPhAT) of 2-phenyl-α-tetralone, 2, are present in dilute THF solution as monomers and dimers with K1.2 = 1810 (1-Cs,

Base-controlled chemoselectivity: direct coupling of alcohols and acetonitriles to synthesise α-alkylated arylacetonitriles or acetamides

We achieved chemoselective synthesis of α-alkylated arylacetonitriles and acetamides by combining Ir complex-catalysed direct coupling of alcohols and nitriles by a simple adjustment of the base. Methanol and ethanol performed well as the alkylating reagents. This method of acetonitrile alkylation provided a novel approach for carbon chain extension.

Atmosphere-Controlled Chemoselectivity: Rhodium-Catalyzed Alkylation and Olefination of Alkylnitriles with Alcohols

The chemoselective alkylation and olefination of alkylnitriles with alcohols have been developed by simply controlling the reaction atmosphere. A binuclear rhodium complex catalyzes the alkylation reaction under argon through a hydrogen-borrowing pathway and the olefination reaction under oxygen through aerobic dehydrogenation. Broad substrate scope is demonstrated, permitting the synthesis of some important organic building blocks. Mechanistic studies suggest that the alkylation product may be formed through conjugate reduction of an alkene intermediate by a rhodium hydride, whereas the formation of olefin product may be due to the oxidation of the rhodium hydride complex with molecular oxygen.