133601-17-9

Basic information

• Product Name: 8-(1-hydroxy-1-phenylmethyl)-1,2,3,4-tetrahydro-1-naphthalenone
• CAS NO: 133601-17-9
• Molecular Weight: 252.313
• Mol File: 133601-17-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-(1-hydroxy-1-phenylmethyl)-1,2,3,4-tetrahydro-1-naphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(1-hydroxy-1-phenylmethyl)-1,2,3,4-tetrahydro-1-naphthalenone(133601-17-9)
• EPA Substance Registry System: 8-(1-hydroxy-1-phenylmethyl)-1,2,3,4-tetrahydro-1-naphthalenone(133601-17-9)

Safety Data

• Hazardous Substances Data: 133601-17-9(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 88058-45-1 8-benzyloxy-1,2,3,4-tetrahydro-1-naphthalenone 
• 7695-47-8 8-hydroxy-1,2,3,4-tetrahydro-1-naphthalenone 

Relevant articles and documents

Photocyclization Reactions. Part 3 [1]. Synthesis of Naphtho[1,8-bc]-furans and Cyclohepta[cd]benzofurans Using Photocyclization of 8-Alkoxy-1,2,3,4-tetrahydro-1-naphthalenones and 4-Alkoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ones

Photocyclization reactions were carried out on 8-alkoxy-1,2,3,4-tetrahydro-1-naphthalenones (six-membered ring ketones) 4a-g and 4-alkoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ones (seven-membered ring ketones) 5a-e in acetonitrile. Irradiation of 4a-f gave rearranged naphthyl alcohols 8a-f as major products. In the case of 4g, 2a,3,4,5-tetrahydronaphtho[1,8-bc]furan-2a-ol 6g was obtained. In contrast, irradiation of 5a-e afforded 2,2a,3,4,5,6-hexahydrocyclohepta[cd]benzofuran-2a-ols 9a-e in good yields. The difference in reactivities between 4a-g and 5a-e is attributed to the conformation of six- and seven-membered rings. Conformational and substituent effects in cyclization step of 1,5-biradicals are discussed along with reaction pathways.