133603-87-9

Basic information

• Product Name: trans-2,3-bis(4-chlorophenyl)piperazine
• Synonyms: trans-2,3-bis(4-chlorophenyl)piperazine
• CAS NO: 133603-87-9
• Molecular Weight: 307.222
• Mol File: 133603-87-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: trans-2,3-bis(4-chlorophenyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2,3-bis(4-chlorophenyl)piperazine(133603-87-9)
• EPA Substance Registry System: trans-2,3-bis(4-chlorophenyl)piperazine(133603-87-9)

Safety Data

• Hazardous Substances Data: 133603-87-9(Hazardous Substances Data)

Upstream product

• 60434-95-9 N,N'-bis(4-chlorobenzylidene)ethane-1,2-diamine 
• 60434-95-9 (1E,1'E)-N,N'-(ethane-1,2-diyl)bis(1-(4-chlorophenyl)methanimine) 

Relevant articles and documents

A simple method of synthesis of (±)-2,3-diarylpiperazines and a novel method of resolution of (±)-2,3-diphenylpiperazine

Intramolecular reductive coupling of diimines in the presence of Zn/Ti(OiPr)2Cl2 gives the corresponding (±)-2,3-diarylpiperazines in 73-83% yields with dl/meso ratio >99%: 1%. The (±)-2,3-diphenylpiperazine obtained in t

Diastereoselective synthesis of piperazines by manganese-mediated reductive cyclization.

A simple and effective synthesis of trans aryl-substituted piperazines using a Bronsted acid and manganese(0) is described. [reaction: see text]