133773-64-5 Usage
Description
(RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is a chemical compound characterized by the molecular formula C15H17NO5. It serves as a protective group for the amino acid serine, with the benzyloxycarbonyl group shielding the reactive functional groups of serine during chemical reactions. (RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is widely utilized in organic synthesis and peptide chemistry, playing a significant role in the pharmaceutical and biotechnology sectors.
Uses
Used in Pharmaceutical Industry:
(RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is used as a protective group for serine in the synthesis of complex organic molecules and peptides. It is crucial for the development of new drugs and biologically active compounds, ensuring the stability and reactivity of the serine molecule during the synthesis process.
Used in Biotechnology Industry:
In the biotechnology field, (RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is employed as a protective agent for serine during the synthesis of bioactive peptides and proteins. (RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid aids in the development of novel therapeutic agents and the study of protein structure and function.
Used in Material Science:
(RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is also utilized in the development of new materials, where its protective properties for serine can be harnessed to create innovative compounds with specific properties and applications.
Used in Protein Structure and Function Studies:
(RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoic acid is essential in the study of protein structure and function, as it allows researchers to manipulate and protect specific amino acid residues, such as serine, during experiments. This capability enables a deeper understanding of protein interactions and mechanisms, which can lead to the discovery of new therapeutic targets and strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 133773-64-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,7,7 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 133773-64:
(8*1)+(7*3)+(6*3)+(5*7)+(4*7)+(3*3)+(2*6)+(1*4)=135
135 % 10 = 5
So 133773-64-5 is a valid CAS Registry Number.
133773-64-5Relevant articles and documents
Synthesis and selective N,O-functionalization of pyrazolone-fused 3-aminoazepinones
Schurgers, Ben,Van Lommen, Guy,Verniest, Guido
, p. 3572 - 3576 (2015)
A new class of pyrazolone-fused 3-amino-1,3,4,7-tetrahydro-2H-azepin-2-ones was synthesized from azepane-based α,β-unsaturated esters. The latter compounds were obtained efficiently from 2-Cbz-amino-N-(2-bromoallyl)-4-pentenamide derivatives through initi
Modified N-acyl-homoserine lactones as chemical probes for the elucidation of plant-microbe interactions
Thomanek, Heike,Schenk, Sebastian T.,Stein, Elke,Kogel, Karl-Heinz,Schikora, Adam,Maison, Wolfgang
, p. 6994 - 7003 (2013/10/08)
Gram-negative bacteria often use N-acyl-homoserine lactones (AHLs) as signal molecules to monitor their local population densities and to regulate gene-expression in a process called "Quorum Sensing" (QS). This cell-to-cell communication allows bacteria to adapt to environmental changes and to behave as multicellular communities. QS plays a key role in both bacterial virulence towards the host and symbiotic interactions with other organisms. Plants also perceive AHLs and respond to them with changes in gene expression or modifications in development. Herein, we report the synthesis of new AHL-derivatives for the investigation and identification of AHL-interacting proteins. We show that our new compounds are still recognised by different bacteria and that a novel biotin-tagged-AHL derivative interacts with a bacterial AHL receptor.
Resolution of non-proteinogenic amino acids via microbial lipase-catalyzed enantioselective transesterification
Miyazawa, Toshifumi,Mio, Motoe,Watanabe, Yuko,Yamada, Takashi
, p. 219 - 224 (2008/09/20)
A number of non-proteinogenic amino acids bearing aliphatic side chains were resolved with moderate to good enantioselectivities (E = 15-42) through the Burkholderia cepacia lipase-catalyzed enantioselective transesterification of the 2,2,2-trifluoroethyl esters of their N-benzyloxycarbonyl derivatives with methanol as a nucleophile in diisopropyl ether.
