133871-69-9

Basic information

• Product Name: Benzaldehyde, 2,4,6-tribromo-3-methoxy-
• CAS NO: 133871-69-9
• Molecular Formula: C8H5Br3O2
• Molecular Weight: 372.839
• Mol File: 133871-69-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2,4,6-tribromo-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,4,6-tribromo-3-methoxy-(133871-69-9)
• EPA Substance Registry System: Benzaldehyde, 2,4,6-tribromo-3-methoxy-(133871-69-9)

Safety Data

• Hazardous Substances Data: 133871-69-9(Hazardous Substances Data)

Upstream product

• 2737-22-6 2,4,6-tribromo-3-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 100-83-4 meta-hydroxybenzaldehyde 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 

Downstream Products

• 607-99-8 2,4,6-tribromoanisole 
• 14753-56-1 4-methoxy-2-carboxy-1,3,5-tribromobenzene 
• 64-18-6 formic acid 
• 487027-13-4 (E)-1,3,5-tribromo-2-methoxy-4-(2-nitrovinyl)benzene 

Relevant articles and documents

N-dealkylative SNAr reaction using aromatic halides: Synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives

An efficient protocol for the synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives has been developed using haloarenes involving N-dealkylative SNAr reaction. The method employs a wide variety of substrates and features the f

N1,N1-dimethyl-N3-(3-(trifluoromethyl) phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis

The natural product, convolutamine I (1), has anti-trypanosomal activity however it has a high molecular weight of 473 due to a presence of 3 bromine atoms. The synthesis of the natural product convolutamine I (1) together with its analogues are presented. A SAR study against Trypanosoma brucei brucei led to compounds with improved physico-chemical properties: lower molecular weight and lower log P while maintaining potency (with a slight 2-fold improvement).

Asymmetric synthesis of amathamides A and B: Novel alkaloids isolated from Amathia wilsoni

Syntheses of the amathamides A and B ((2S)-N-[(E and Z)-2(2,4-dibromo-5-methoxyphenylethenyl]-1-methyl-2-pyrrolinecarboxamides), new alkaloids isolated from the Tasmanian marine bryozoan Amathia wilsoni, were accomplished by a sequence of reactions starting from 3-hydroxybenzaldehyde.