13389-51-0

Basic information

• Product Name: (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE
• Synonyms: (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE
• CAS NO: 13389-51-0
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.68894
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 13389-51-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 71.5–72°C
• Boiling Point: 386.4°C at 760 mmHg
• Flash Point: 160.8°C
• Appearance: /
• Density: 1.212g/cm³
• Vapor Pressure: 3.56E-06mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE(13389-51-0)
• EPA Substance Registry System: (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE(13389-51-0)

Safety Data

• Hazardous Substances Data: 13389-51-0(Hazardous Substances Data)

Usage

Description

(3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE is a 4-methoxybenzophenone derivative that exhibits plant growth regulating activity. As a solid chemical compound, it has the ability to inhibit shoot and root growth, induce chlorosis, and cause disturbances in phototropism or geotropism.

Uses

Used in Agriculture:
(3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE is used as a plant growth regulator for controlling shoot and root growth in various crops. Its ability to inhibit growth can be beneficial in managing plant size and density, as well as promoting healthier growth patterns.
Used in Plant Research:
In the field of plant biology, (3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE is used as a research tool to study the effects of chemical compounds on plant growth and development. Its ability to induce chlorosis and disturb phototropism or geotropism can provide valuable insights into the underlying mechanisms of these processes.
Used in Pest Control:
(3-CHLORO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE can be used as a component in pest control formulations to manage unwanted plant growth and reduce the need for chemical herbicides. Its targeted effects on plant growth can help control invasive species or overgrown plants in certain environments.

InChI:InChI=1/C14H11ClO2/c1-17-13-7-5-10(6-8-13)14(16)11-3-2-4-12(15)9-11/h2-9H,1H3

Upstream product

• 18780-05-7 (p-chlorobenzoyl)pentamethylbenzene 
• 100-66-3 methoxybenzene 
• 94055-44-4 (3-Chloro-phenyl)-(10-methyl-anthracen-9-yl)-methanone 
• 618-46-2 m-Chlorobenzoyl chloride 
• 535-80-8 3-chlorobenzoate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 66938-41-8 3-chloro-3'-nitro-4'-methoxybenzophenone 
• 61002-52-6 3-chlorophenyl 4-hydroxyphenyl ketone 
• 812684-99-4 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane 
• 66938-61-2 (4-amino-3-nitrophenyl)-3-chlorophenylmethanone 
• 172282-46-1 4-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1,2-benzenediamine 
• 204255-40-3 (4-amino-3-nitrophenyl)-3-chlorophenylmethanol 
• 171849-14-2 4-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-2-nitro-phenylamine 
• 115575-11-6 liarozole 

Relevant articles and documents

Palladium on magnetic Irish moss: A new nano-biocatalyst for suzuki type cross-coupling reactions

A novel heterogeneous magnetic palladium nano-biocatalyst was designed by utilizing Irish moss, a family of sulfated polysaccharides extracted from algae, as a natural biopolymer. This magnetic Irish moss decorated with palladium (Pd–Fe3O4@IM) to form a biomagnetic catalytic system was synthesized and well characterized by FT–IR analysis, X-ray powder diffraction, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, atomic absorption spectroscopy and transmission electron microscopy. The catalyst was stable to air and moisture and displayed high catalytic activity in ligand-free Suzuki–Miyaura cross-coupling reactions conducted under green chemistry reaction conditions. The aromatic ketones are produced by the cross-coupling reaction between acid chlorides and aryl boronic acid derivatives in high yields.

Generation of Aryl and Heteroaryl Magnesium Reagents in Toluene by Br/Mg or Cl/Mg Exchange

The alkylmagnesium alkoxide sBuMgOR?LiOR (R=2-ethylhexyl), which was prepared as a 1.5 m solution in toluene, undergoes very fast Br/Mg exchange with aryl and heteroaryl bromides, producing aryl and heteroaryl magnesium alkoxides (ArMgOR?LiOR) in toluene. These Grignard reagents react with a broad range of electrophiles, including aldehydes, ketones, allyl bromides, acyl chlorides, epoxides, and aziridines, in good yields. Remarkably, the related reagent sBu2Mg?2 LiOR (R=2-ethylhexyl) undergoes Cl/Mg exchange with various electron-rich aryl chlorides in toluene, producing diorganomagnesium species of type Ar2Mg?2 LiOR, which react well with aldehydes and allyl bromides.

Synthesis and biological evaluation of negative allosteric modulators of the Kv11.1(hERG) channel

We synthesized and evaluated a series of compounds for their allosteric modulation at the Kv11.1 (hERG) channel. Most compounds were negative allosteric modulators of [3H]dofetilide binding to the channel, in particular 7f, 7h-j and 7p. Compounds 7f and 7p were the most potent negative allosteric modulators amongst all ligands, significantly increasing the dissociation rate of dofetilide in the radioligand kinetic binding assay, while remarkably reducing the affinities of dofetilide and astemizole in a competitive displacement assay. Additionally, both 7f and 7p displayed peculiar displacement characteristics with Hill coefficients significantly distinct from unity as shown by e.g., dofetilide, further indicative of their allosteric effects on dofetilide binding. Our findings in this investigation yielded several promising negative allosteric modulators for future functional and clinical research with respect to their antiarrhythmic propensities, either alone or in combination with known Kv11.1 blockers.