618-46-2

Basic information

• Product Name: m-Chlorobenzoyl chloride
• Synonyms: Benzoylchloride, m-chloro- (6CI,7CI,8CI);NSC 41886;m-Chlorobenzoyl chloride;M-Chlorobenzoyl Chloride Enquiry
• CAS NO: 618-46-2
• Molecular Formula: C7H4Cl2O
• Molecular Weight: 175.01206
• EINECS: 210-552-6
• Mol File: 618-46-2.mol
• Article Data: 126

Chemical Properties

• Boiling Point: 225 °C at 760 mmHg
• Flash Point: 88.8 °C
• Appearance: clear colourless liquid
• Density: 1.369 g/cm³
• Refractive Index: 1.568-1.57
• CAS DataBase Reference: m-Chlorobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: m-Chlorobenzoyl chloride(618-46-2)
• EPA Substance Registry System: m-Chlorobenzoyl chloride(618-46-2)

Safety Data

• Hazard Codes: C:Corrosive
• Statements: R34:
• Safety Statements: S26:; S28A:
• Hazardous Substances Data: 618-46-2(Hazardous Substances Data)

Usage

General Description

m-Chlorobenzoyl chloride, also known as meta-chlorobenzoyl chloride, is a chemical compound with the formula C7H4Cl2O. It is a colorless to pale yellow liquid with a pungent odor and is used as a reagent in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is an acyl chloride, which means it contains a functional group composed of a carbonyl center bonded to a chlorine atom. m-Chlorobenzoyl chloride is highly reactive and can cause severe irritation to the eyes, skin, and respiratory system upon contact. It should be handled with care and used in a well-ventilated environment.

InChI:InChI=1/C7H4Cl2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H

Upstream product

• 121-53-9 3-sulfosalicylic acid 
• 77-95-2 1,3,4,5-tetrahydroxy-cyclohexanecarboxylic acid 
• 98-88-4 benzoyl chloride 
• 535-80-8 3-chlorobenzoate 
• 10026-13-8 phosphorus pentachloride 
• 77-95-2 D-(-)-quinic acid 
• 2136-81-4 3-chlorobenzotrichloride 
• 756-79-6 dimethyl methane phosphonate 
• 115377-62-3 1-benzyl-4-amino-1H-imidazole-5-carboxamide 
• 3416-93-1 2-(4,5-Dihydro-1,3-oxazol-2-yl)aniline 
• 873-63-2 m-chlorobenzyl alcohol 
• 766-84-7 3-chloro-benzonitrile 
• 1128-76-3 3-chloro-benzoic acid ethyl ester 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 104176-96-7 3-{3-chloro-α-[5-(2-hydroxy-benzofuran-3-yl)-penta-2,4-dienylidenamino]-benzylidene}-3H-benzofuran-2-one 
• 2905-65-9 methyl 3-chlorobenzoate 
• 1128-76-3 3-chloro-benzoic acid ethyl ester 
• 124105-50-6 N,N'-bis-[2-(3-chloro-benzoyloxy)-ethyl]-terephthalamide 
• 125553-47-1 3-chloro-benzoic acid-((1R)-menthyl ester) 
• 6280-51-9 2-methylphenyl 3-chlorobenzoate 
• 71267-16-8 N-(4-nitrophenyl)-3-chlorophenyl carboxamide 
• 24167-52-0 N,N-dimethyl-3-chlorobenzamide 
• 57800-68-7 3'-Chlor-2,4-dimethyl-benzophenon 
• 78154-49-1 o-phenol 
• 13395-60-3 (3-chlorophenyl)(4-methylphenyl)methanone 
• 57728-59-3 m-chlorobenzene carboxamidoacetic acid 
• 18370-10-0 3-chloro-N-methyl-benzamide 
• 39651-00-8 Cyclohexyl 3-chlorobenzoate ester 

Relevant articles and documents

4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

4-phenyl-N-(phenyl)thiazol-2-amine and 4-(pyridin-3-yl)-N-( phenyl) thiazol-2-amine derivatives and the corresponding thiadiazole, thiophene, oxazole, oxadiazole, imidazole and triazole derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders.

Ru-Catalyzed C(sp2)?H Bond Arylation of Benzamides Bearing a Novel 4-Aminoantipyrine as a Directing Group

A novel design-based removable N,O-bidentate directing group based on cheap and commercially available 4-aminoantipyrine (AAP) is reported. Aromatic AP amides bearing 4-aminoantipyrine underwent efficient Ru-catalyzed C(sp2)?H arylation using [RuCl2(PPh3)3] as a catalyst and aryl bromides as electrophiles. The novel bidentate directing group enabled the C?H functionalization reaction with good scope, good functional group tolerance and in decent yields.

NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

Provided is a heterocyclic compound Chemical Formula 1 or 2: and an organic light emitting device comprising the same.