18370-10-0

Basic information

• Product Name: 3-Chloro-N-methylbenzamide ,98%
• Synonyms: 3-Chloro-N-methylbenzamide ,98%;3-Chloro-N-MethylbenzaMide, 97%;BenzaMide, 3-chloro-N-Methyl-
• CAS NO: 18370-10-0
• Molecular Formula: C₈H₈ClNO
• Molecular Weight: 169.60822
• Mol File: 18370-10-0.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Chloro-N-methylbenzamide ,98%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-N-methylbenzamide ,98%(18370-10-0)
• EPA Substance Registry System: 3-Chloro-N-methylbenzamide ,98%(18370-10-0)

Safety Data

• Statements: 20/22-36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 18370-10-0(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 74-89-5 methylamine 
• 71-23-8 propan-1-ol 
• 535-80-8 3-chlorobenzoate 
• 2905-65-9 methyl 3-chlorobenzoate 
• 832695-88-2 3-(methylcarbamoyl)phenylboronic acid 
• 593-51-1 methylamine hydrochloride 
• 30004-67-2 N,S-dimethyl-S-phenylsulfoximine 
• 587-04-2 m-Chlorobenzaldehyde 
• 67-56-1 methanol 
• 618-48-4 3-chlorobenzamide 
• 766-84-7 3-chloro-benzonitrile 
• 34158-71-9 3-chlorobenzaldehyde oxime 
• 109-09-1 2-chloropyridine 

Downstream Products

• 90278-24-3 5-(3-chloro-phenyl)-1-methyl-1H-tetrazole 
• 40763-96-0 2-nitro-5-chlorobenzamide 
• 1235478-95-1 7-methoxy-2-methyl-3,4-diphenylisoquinolin-1(2H)-one 
• 1403951-57-4 7-chloro-2-methyl-3,4-diphenylisoquinolin-1(2H)-one 
• 1613320-03-8 4-chloro-2-(methylcarbamoyl)phenyl 4-chlorobenzoate 
• 284461-73-0 sorafenib 
• 755037-03-7 regorafenib 
• 1016-78-0 3-chlorobenzophenone 

Relevant articles and documents

Palladium-Catalyzed Direct C-H Trifluoroethylation of Aromatic Amides

A simple and direct C-H trifluoroethylation of aromatic amides has been developed. The protocol is applicable to a variety of aromatic amides, including ones derived from amino acids. The developed method can be used for further modifications of peptides. Preliminary mechanistic studies have been done by isolating the reaction intermediate.

The Pd-catalyzed synthesis of difluoroethyl and difluorovinyl compounds with a chlorodifluoroethyl iodonium salt (CDFI)

Herein, we report a simple and efficient method for the direct installation of chlorodifluoroethyl group onto aromatic molecules of various aromatic amides with a new 2-chloro,2,2-difluoroethyl(mesityl)iodonium salt (CDFI). Moreover, the chlorodifluoroeth

Formation of Aryl [1-Cyano-4-(dialkylamino)butadienyl] Ketones from Pyridines

Treatment of 2-chloropyridine with LDA and the Weinreb amide of benzoic acid afforded three unusual products, namely N -methylbenzamide, 2-chloropyridine-3-methanol, and the ring-opened addition product. This same final product could also be obtained from 2-chloro-3-benzoylpyridine on treatment with LDA. Mechanistic insight for the formation of these products is provided.