134100-03-1

Basic information

• Product Name: 1-(3-deoxy-3-phenylseleno-2,5-di-O-pivaloyl-β-D-xylofuranosyl)uracil
• Synonyms: 1-(3-deoxy-3-phenylseleno-2,5-di-O-pivaloyl-β-D-xylofuranosyl)uracil
• CAS NO: 134100-03-1
• Molecular Weight: 551.498
• Mol File: 134100-03-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-deoxy-3-phenylseleno-2,5-di-O-pivaloyl-β-D-xylofuranosyl)uracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-deoxy-3-phenylseleno-2,5-di-O-pivaloyl-β-D-xylofuranosyl)uracil(134100-03-1)
• EPA Substance Registry System: 1-(3-deoxy-3-phenylseleno-2,5-di-O-pivaloyl-β-D-xylofuranosyl)uracil(134100-03-1)

Safety Data

• Hazardous Substances Data: 134100-03-1(Hazardous Substances Data)

Upstream product

• 1666-13-3 diphenyl diselenide 
• 134100-02-0 3'-O-mesyl-2',5'-di-O-pivaloyluridine 

Downstream Products

• 134100-05-3 Propionic acid (2R,3S,4S,5R)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-phenylselanyl-tetrahydro-furan-3-yl ester 
• 134100-19-9 Acetic acid (2R,3S,5S)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-[1-phenyl-meth-(E)-ylidene]-tetrahydro-furan-3-yl ester 
• 134100-14-4 Acetic acid (2R,3S,4R,5S)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(hydroxy-phenyl-methyl)-tetrahydro-furan-3-yl ester 
• 134100-04-2 Acetic acid (2R,3S,4S,5R)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-phenylselanyl-tetrahydro-furan-3-yl ester 
• 134100-08-6 1-[(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(hydroxy-phenyl-methyl)-3-oxo-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 
• 134100-16-6 1-{(2R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3-oxo-4-[1-phenyl-meth-(E)-ylidene]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione 
• 135928-55-1 1-[(2R,3S,4R,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3-hydroxy-4-phenylselanyl-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 
• 134100-23-5 1-[(2R,4R,5S)-4-Benzyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-oxo-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 
• 142706-48-7 1-((2R,3S,4R,5R)-3-Hydroxy-5-hydroxymethyl-4-phenylselanyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 
• 136409-75-1 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-3-phenylseleno-β-D-xylofuranosyl>uracil 
• 132364-17-1 1-[5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pento-2-enofuranosyl]uracil 

Relevant articles and documents

Uracil and Adenine Nucleosides Having a 2',3'-Bromovinyl Structure: Highly Versatile Synthons for the Synthesis of 2'-C- and 3'-C-Branched 2',3'-Unsaturated Derivatives

Preparation of 2'- and 3'-bromo derivatives of 2',3'-unsaturated uracil and adenine nucleosides has been carried out starting from the corresponding β-hydroxyselenides by way of bromination and successive selenoxide elimination.These compounds have been shown to serve as versatile synthons for the preparation of anti-HIV candidates, 2'-C- and 3'-C-branched 2',3'-unsaturated nucleosides, through palladium-catalyzed cross-coupling and halogen-lithium exchange reactions. Key Words: β-hydroxyselenide; bromovinyl structure; branched-sugar nucleoside; anti-HIV agent; 2',3'-unsaturated nucleoside.