135928-55-1Relevant articles and documents
2′,3′-Cyclopropanated Nucleoside Dimers
Yannopoulos, Constantin G.,Zhou, Wen-Qiang,Nower, Peter,Peoc'h, Didier,Sanghvi, Yogesh S.,Just, George
, p. 378 - 380 (2007/10/03)
Syntheses of three novel conformationally rigid dimers containing cyclopropyl -amide and -sulfonamide functionalities are described. Their incorporation into an oligonucleotide sequence resulted in considerable lowering of the Tm's in binding to their complementary RNA sequences.
Nucleosidic enol esters: A versatile tool for the synthesis of 3'-carbon-substituted nucleosides
Haraguchi,Tanaka,Itoh,Miyasaka
, p. 777 - 780 (2007/10/02)
Enol esters of uracil and adenine nucleosides prepared by selenoxide fragmentation of the corresponding 3'-phenylseleno derivatives have been shown to yield 3'-carbon-substituted products upon reacting with MeLi followed by electrophiles, providing the fi