1341155-49-4

Basic information

• Product Name: C₁₈H₁₇N₃O₂
• CAS NO: 1341155-49-4
• Molecular Weight: 307.352
• Mol File: 1341155-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇N₃O₂(1341155-49-4)
• EPA Substance Registry System: C₁₈H₁₇N₃O₂(1341155-49-4)

Safety Data

• Hazardous Substances Data: 1341155-49-4(Hazardous Substances Data)

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 941-55-9 4-toluenesulfonyl azide 
• 5405-17-4 N-benzyl-3-methylaniline 

Downstream Products

• 1341156-06-6 1-benzyl-3-(1-hydroxyethylidene)-6-methylindolin-2-one 
• 1621686-48-3 3-acetyl-1-benzyl-4-methylindolin-2-one 

Relevant articles and documents

Aqueous copper nitrate catalyzed synthesis of 3-alkylideneoxindoles from α-diazo-ketoanilides

An economical, practical, and green protocol with which to synthesize 3-alkylideneoxindoles from α-diazo-ketoanilides has been developed. The approach employs inexpensive Cu(NO3)2·3H 2O as catalyst and environmentally friendly water as solvent, and achieves moderate to excellent yields. The method has good tolerance to a range of N-alkyl and N-aryl groups, including electron-withdrawing and electron-donating groups on the aromatic ring, ortho-, meta-, and para-substituents, and -aliphatic and -aromatic keto groups. A plausible mechanism involving intramolecular aromatic metal carbene electrophilic addition as the key step is proposed. Inexpensive Cu(NO3)2· 3H2O catalyst and environmentally friendly water solvent are employed for the transformation of α-diazo-ketoanilides into 3-alkylidene- oxindoles. The process is easily handled, economical, environmentally friendly, and can be used to convert a broad range of substrates in moderate to excellent yields. An intramolecular aromatic metal carbene electrophilic addition mechanism is proposed. Copyright