134440-92-9

Basic information

• Product Name: (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid
• Synonyms: (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid
• CAS NO: 134440-92-9
• Molecular Weight: 431.572
• Mol File: 134440-92-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid(134440-92-9)
• EPA Substance Registry System: (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid(134440-92-9)

Safety Data

• Hazardous Substances Data: 134440-92-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 180133-63-5 (4S,5S,2E)-2-iodo-5-methoxy-4-methyl-6-phenyl-2-hexene 
• 126399-05-1 cis/trans-(4S,5S)-5-methoxy-2,4-dimethyl-6-phenylhex-2-en-1-ol 
• 126399-06-2 ((E)-(4S,5S)-5-Methoxy-2,4-dimethyl-6-phenyl-hex-2-enyl)-triphenyl-phosphonium; bromide 
• 126399-11-9 cis/trans-(4S,5S)-1-bromo-5-methoxy-2,4-dimethyl-6-phenylhex-2-ene 
• 126399-03-9 cis/trans-(4S,5S)-ethyl-5-methoxy-2,4-dimethyl-6-phenylhex-2-enoate 
• 137172-56-6 ((3R,4S)-4-Methyl-5-oxo-tetrahydro-furan-3-yl)-carbamic acid tert-butyl ester 
• 177019-70-4 (E)-(2S,3R)-2-Methoxy-3-methyl-hex-4-enoic acid methyl ester 
• 177019-69-1 (E)-(2S,3R)-2-Hydroxy-3-methyl-hex-4-enoic acid methyl ester 
• 67279-64-5 (E)-(2S,3R)-2-Methoxy-3-methyl-hex-4-enoic acid 
• 1027286-43-6 (2S,3R)-3-tert-Butoxycarbonylamino-3-ethylsulfanylcarbonyl-2-methyl-propionic acid methyl ester 
• 180133-62-4 (4S,5S)-5-methoxy-6-phenyl-2-hexyn-4-ol 
• 188295-04-7 (2S)-2-hydroxy-N-methoxy-N-methyl-3-phenylpropanamide 
• 165277-59-8 (S)-2,N-Dimethoxy-N-methyl-3-phenyl-propionamide 

Downstream Products

• 225781-02-2 Boc-Adda-D-iso-Glu(OMe)-N-(Me)-Gly-D-Ala-L-Leu-D-β-Me-iso-Asp(OMe)-L-Ala-OH 
• 225781-01-1 Boc-Adda-D-iso-Glu(OMe)-N-(cyclohexyl)-Gly-D-Ala-L-Leu-D-β-Me-iso-Asp(OMe)-L-Ala-OH 
• 225780-68-7 Boc-Adda-D-iso-Glu(OMe)-MeΔAla-D-Ala-3-cyclohexyl-L-Ala-D-β-Me-iso-Asp(OMe)-L-Ala-OH 
• 225781-00-0 Boc-Adda-D-iso-Glu(OMe)-MeΔAla-N²-Boc-N³-Troc-(R)-aminoala-L-Leu-D-β-Me-iso-Asp(OMe)-L-Ala-OH 
• 610284-43-0 (2S,5R)-1-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoyl)-pyrrolidine-2,5-dicarboxylic acid dimethyl ester 
• 223923-83-9 Dimethylmotuporin 
• 223923-68-0 (2S,3R)-2-{[(R)-4-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-methoxycarbonyl-butyryl]-methyl-amino}-3-hydroxy-butyric acid 
• 223923-94-2 (2S,5R,6S,9R,12S,13S,16R)-9-Isopropyl-12-((1E,3E)-(5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,2,6,13-tetramethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentaaza-cyclononadecane-5,16-dicarboxylic acid dimethyl ester 
• 223923-93-1 (2S,5R,6S,9S,12S,13S,16R)-9-Isopropyl-12-((1E,3E)-(5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,2,6,13-tetramethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentaaza-cyclononadecane-5,16-dicarboxylic acid dimethyl ester 
• 223923-92-0 3-(1-allyloxycarbonyl-2-methyl-propylcarbamoyl)-2-(2-{[4-(3-tert-butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-methoxycarbonyl-butyryl]-methyl-amino}-propionylamino)-butyric acid methyl ester 
• 223924-04-7 2-[3-(2-{[4-(3-tert-butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-methoxycarbonyl-butyryl]-methyl-amino}-3-hydroxy-butyrylamino)-3-methoxycarbonyl-2-methyl-propionylamino]-3-methyl-butyric acid 
• 223923-79-3 3-(1-allyloxycarbonyl-2-methyl-propylcarbamoyl)-2-(2-{[4-(3-tert-butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-methoxycarbonyl-butyryl]-methyl-amino}-but-2-enoylamino)-butyric acid methyl ester 
• 223924-03-6 3-(1-allyloxycarbonyl-2-methyl-propylcarbamoyl)-2-(2-{[4-(3-tert-butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-methoxycarbonyl-butyryl]-methyl-amino}-3-hydroxy-butyrylamino)-butyric acid methyl ester 

Relevant articles and documents

Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays

A series of simplified microcystin-LR analogues based on Adda [(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid] or its corresponding aldol precursor linked to a polypeptide moiety have been synthesised and assessed for thei

Enantiospecific synthesis of N-Boc-Adda: a linear approach.

[structure: see text] Synthesis of the unusual amino acid (2S,3S,8S, 9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid (Adda), a unit of numerous cyanobacterial toxins, is described. Construction of the target molecule was achieved in 1

An asymmetric synthesis of ADDA, and ADDA-glycine dipeptide using the ss-lactam synthon method

The paper describes the synthesis of the W-Boc lactam 4, and demonstrates that it is an important intermediate in the synthesis of dipeptide 5 (X = H, n = 0, R = Me), an analogue of the ADDA-GIu dipeptide 3. In addition we have described a mild method for the preparation of the amino acid salt ADDA-HC1, and provided synthetic methods, and full characterisation for the previously 'elusive' free amino acid ADDA.