610284-43-0

Basic information

• Product Name: (2S,5R)-1-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoyl)-pyrrolidine-2,5-dicarboxylic acid dimethyl ester
• CAS NO: 610284-43-0
• Molecular Weight: 600.753
• Mol File: 610284-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,5R)-1-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoyl)-pyrrolidine-2,5-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-1-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoyl)-pyrrolidine-2,5-dicarboxylic acid dimethyl ester(610284-43-0)
• EPA Substance Registry System: (2S,5R)-1-((4E,6E)-(2S,3S,8S,9S)-3-tert-Butoxycarbonylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoyl)-pyrrolidine-2,5-dicarboxylic acid dimethyl ester(610284-43-0)

Safety Data

• Hazardous Substances Data: 610284-43-0(Hazardous Substances Data)

Upstream product

• 134440-92-9 (2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid 
• 116836-63-6 cis-2,5-dimethyl pyrrolidine-2,5-dicarboxylate 

Relevant articles and documents

Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors

A series of greatly simplified microcystin analogues comprised only of Adda (the β-amino acid common to the microcystins, nodularins, and motuporin,) and a single additional amino acid residue was synthesized and screened for inhibition of the protein phosphatases 1 and 2A. Several of the analogues were shown to be mid-nanomolar inhibitors of the enzymes.