1345249-31-1

Basic information

• Product Name: C₂₇H₃₁ClN₂O₅
• CAS NO: 1345249-31-1
• Molecular Weight: 499.007
• Mol File: 1345249-31-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₁ClN₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₁ClN₂O₅(1345249-31-1)
• EPA Substance Registry System: C₂₇H₃₁ClN₂O₅(1345249-31-1)

Safety Data

• Hazardous Substances Data: 1345249-31-1(Hazardous Substances Data)

Upstream product

• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 1252761-95-7 (R)-4-(4-chloro-3-iodophenyl)pyrrolidin-2-one 
• 1252761-51-5 (R)-4-(4-chloro-3-nitrophenyl)pyrrolidin-2-one 
• 1252761-96-8 tert-butyl (4R)-4-[4-chloro-3-(4,4,5,5-tetramethyl(1,3,2-dioxaborolan-2-yl))phenyl]-2-oxopyrrolidinecarboxylate 
• 1252761-21-9 (R)-4-(3-amino-4-chlorophenyl)pyrrolidin-2-one 
• 5632-16-6 4-(bromomethyl)quinoline 
• 64-17-5 ethanol 
• 1252762-31-4 tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate 

Downstream Products

• 1345248-99-8 C₂₀H₁₉ClN₂O₃ 

Relevant articles and documents

Discovery of a novel potent GABAB receptor agonist

Structure-activity studies have led to a discovery of 3-(4-pyridyl)methyl ether derivative 9d that has 25-to 50-fold greater functional potency than R-baclofen at human and rodent GABAB receptors in vitro. Mouse hypothermia studies confirm that this compound crosses the blood-brain barrier and is approximately 50-fold more potent after systemic administration.