134541-08-5

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,5-(methoxymethyl)-(9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,5-(methoxymethyl)-(9CI);5-(Methoxymethyl)
• CAS NO: 134541-08-5
• Molecular Formula: C₆H₇NO₄
• Molecular Weight: 157.124
• Product Categories: OXAZOLE
• Mol File: 134541-08-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 69-70 °C
• Boiling Point: 300.5±27.0 °C(Predicted)
• Appearance: /
• Density: 1.341±0.06 g/cm3(Predicted)
• PKA: 2.94±0.36(Predicted)
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,5-(methoxymethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,5-(methoxymethyl)-(9CI)(134541-08-5)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,5-(methoxymethyl)-(9CI)(134541-08-5)

Safety Data

• Hazardous Substances Data: 134541-08-5(Hazardous Substances Data)

Upstream product

• 134540-99-1 methyl 5-(methoxymethyl)isoxazole-4-carboxylate 
• 127958-23-0 (Z)-methyl 2-((dimethylamino)methylene)-4-methoxy-3-oxobutanoate 
• 41051-15-4 4-methoxyacetoacetic acid methylester 
• 127958-23-0 methyl 2-[(dimethylamino)methylene]-4-methoxy-3-oxobutanoate 

Downstream Products

• 136995-25-0 5-Methoxymethyl-isoxazole-4-carboxylic acid (4-trifluoromethyl-phenyl)-amide 
• 1076245-65-2 N-{6-amino-5-[2-(trifluoromethoxy)phenyl]pyrazin-2-yl}-5-(methoxymethyl)isoxazole-4-carboxamide 
• 1058722-46-5 C₁₂H₉F₃N₂O₃ 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERIODONTITIS AND RHEUMATOID ARTHRITIS

The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of periodontitis and rheumatoid arthritis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.

PYRIDINE DERIVATIVES

The present invention relates to compounds of the formula (I): (I) and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds for the treatment of pain.