1345412-61-4

Basic information

• Product Name: (R)-1-(1-naphthyl)propyl diphenylacetate
• Synonyms: (R)-1-(1-naphthyl)propyl diphenylacetate
• CAS NO: 1345412-61-4
• Molecular Weight: 380.486
• Mol File: 1345412-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(1-naphthyl)propyl diphenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(1-naphthyl)propyl diphenylacetate(1345412-61-4)
• EPA Substance Registry System: (R)-1-(1-naphthyl)propyl diphenylacetate(1345412-61-4)

Safety Data

• Hazardous Substances Data: 1345412-61-4(Hazardous Substances Data)

Upstream product

• 117-34-0 2,2-diphenylacetic acid 
• 56620-47-4 1-(1-naphthyl)-1-propanol 

Relevant articles and documents

(R)-(+)-N-methylbenzoguanidine ((R)-NMBG) catalyzed kinetic resolution of racemic secondary benzylic alcohols with free carboxylic acids by asymmetric esterification

(R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) was found to function as an efficient acyl-transfer catalyst for the kinetic resolution of racemic secondary benzylic alcohols in the presence of achiral carboxylic acids and pivalic anhydride. The use of a tertiary amine in this reaction is not necessary to attain good chemical yields of the products. It was determined that diphenylacetic acid could be employed as the most suitable acyl donor for achieving a high enantioselectivity for the kinetic resolution of the racemic secondary benzylic alcohols having normal aliphatic alkyl chains at the C-1 positions. On the other hand, a less-hindered carboxylic acid, such as 3-phenylpropanoic acid, functioned as a better acyl donor for the kinetic resolution of racemic secondary benzylic alcohols having branched aliphatic alkyl chains at the C-1 positions.