56620-47-4

Basic information

• Product Name: 1-Naphthalenemethanol, a-ethyl-
• Synonyms: (R)-(-)-1-(α-naphthyl)-1-propanol;(R)-1-(α-naphthyl)-1-propanol;(R)-(+)-1-(1'-naphthyl)-1-propanol;(1R)-1-(naphthalen-1-yl)propan-1-ol;(R)-1-(naphthalen-1-yl)propan-1-ol;(R)-naphthalen-1-yl-ethyl-methanol
• CAS NO: 56620-47-4
• Molecular Formula: C13H14O
• Molecular Weight: 186.25000
• Mol File: 56620-47-4.mol
• Article Data: 199

Chemical Properties

• Boiling Point: 171 °C(Press: 13 Torr)
• Density: 1.0899 g/cm3
• CAS DataBase Reference: 1-Naphthalenemethanol, a-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenemethanol, a-ethyl-(56620-47-4)
• EPA Substance Registry System: 1-Naphthalenemethanol, a-ethyl-(56620-47-4)

Safety Data

• Hazardous Substances Data: 56620-47-4(Hazardous Substances Data)

Upstream product

• 123-38-6 propionaldehyde 
• 703-55-9 1-naphthylmagnesiumbromide 
• 557-20-0 diethylzinc 
• 66-77-3 1-naphthaldehyde 
• 536-74-3 phenylacetylene 
• 941-98-0 1'-naphthacetophenone 
• 67-56-1 methanol 
• 111-71-7 heptanal 
• 2876-63-3 1-naphthyl ethyl ketone 
• 925-90-6 ethylmagnesium bromide 
• 61619-02-1 1-(1'-naphthyl)-allylalcohol 
• 117-34-0 2,2-diphenylacetic acid 
• 2386-64-3 ethylmagnesium chloride 
• 760-19-0 Et₂AlBr 

Downstream Products

• 1565-74-8 (R)-1-phenyl-1-propanol 
• 613-87-6 (S)-1-phenyl-1-propanol 
• 1345412-61-4 (R)-1-(1-naphthyl)propyl diphenylacetate 
• 56620-47-4 (R)-1-(1-naphthyl)propanol 
• 56620-47-4 (S)-1-naphthalen-1-yl-propan-1-ol 
• 1426578-45-1 N-(1-(naphthalen-1-yl)propyl)-4-nitroaniline 
• 149854-36-4 α-Ethyl-1-naphthalinmethanamin-Hydrochlorid 

Relevant articles and documents

Nickel-Catalyzed Ring-Opening C-O Functionalization of peri-Xanthenoxanthenes for 8-Substituted Binaphthol Synthesis

Herein, we disclose the Ni-catalyzed ring-opening C-O functionalization of peri-xanthenoxanthenes using Grignard reagents that forms 8-monofunctionalized binaphthols. 1,2-Bis(dicyclohexylphosphino)ethane was the best ligand for alkylations and ICy for arylation. After mechanistic investigations, we assumed that the reaction proceeds via C-O reduction and subsequent C-O functionalization. To verify the mechanism, the intermediate after reduction was isolated. Moreover, the asymmetric addition, using 8-octylbinaphthol after optical resolution, was studied.

PQXdpap: Helical Poly(quinoxaline-2,3-diyl)s Bearing 4-(Dipropylamino)pyridin-3-yl Pendants as Chirality-Switchable Nucleophilic Catalysts for the Kinetic Resolution of Secondary Alcohols

Helically chiral poly(quinoxaline-2,3-diyl)s bearing 4-(dipropylamino)pyridin-3-yl pendants at the 5-position of the quinoxaline ring (PQXdpap) exhibited high catalytic activities and moderate to high selectivities (up to s = 87) in the acylative kinetic resolution of secondary alcohols. The solvent-dependent helical chirality switching of PQXdpap between pure toluene and a 1:1 mixture of toluene and 1,1,2-trichloroethane enabled the preparation of either compound of a pair of enantiomerically pure alcohols (>99% ee) from a single catalyst.

Chiral P,N-ligands for the highly enantioselective addition of diethylzinc to aromatic aldehydes

A new sterically hindered chiral P,N-ligand was synthesized and successfully applied to copper catalyzed asymmetric addition of diethylzinc to aromatic aldehydes. Various aromatic aldehydes can react smoothly to give the corresponding addition products with good to excellent enantioselectivities, which provides a readily accessible method for the preparation of chiral secondary alcohols.